{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T14:58:25Z","timestamp":1785941905066,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T00:00:00Z","timestamp":1516579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>In\u2010office laryngology procedures are important in the treatment of voice and swallowing disorders. Patient tolerance determines which procedures can be performed without sedation or formal anesthesia. This study examines pain perception during and after in\u2010office vocal fold injection augmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients scheduled for office\u2010based vocal fold injection augmentation were prospectively enrolled at an academic voice center. The short\u2010form McGill Pain Questionnaire was administered before, during, and after the procedure and on postprocedure days 1, 3, and 7. Pre\u2010 and postprocedure vital signs were recorded and heart rate was continuously monitored. Telephone questionnaires were completed on postprocedure days 1 and 3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010five patients consented to participate in our study (24 males, mean age 61 years). Most patients experienced mild to moderate pain with increasing heart rate during the procedure. Pain remained or increased 20 minutes after the procedure and improved but persisted for 1 day. Sensory and affective discomfort was endorsed by the majority. A minority of patients experienced bruising and changes in swallowing with diet modification for 3 days after the procedure. Sixteen percent had discomfort after 1 week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first prospective study examining patient perception of pain during and after in\u2010office injection augmentation using a validated scale and pain descriptors with extended follow\u2010up. The results may offer guidance for patient counseling, consent, and treatment to improve tolerance and success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 128:929\u2013934, 2018<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27061","type":"journal-article","created":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T16:33:07Z","timestamp":1516638787000},"page":"929-934","source":"Crossref","is-referenced-by-count":18,"title":["Perception and duration of pain after office\u2010based vocal fold injection augmentation"],"prefix":"10.1002","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1011-0433","authenticated-orcid":false,"given":"Brianna K.","family":"Crawley","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salem","family":"Dehom","sequence":"additional","affiliation":[{"name":"Voice and Swallowing Center, School of Public Health Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Kutzner","sequence":"additional","affiliation":[{"name":"School of Medicine Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Murry","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0156-978X","authenticated-orcid":false,"given":"Priya","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation\/Pain Management Loma Linda University Health Loma Linda California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20737"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3282f23088"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198506000-00002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(87)91074-8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(76)90113-5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000250898.82268.39"},{"key":"e_1_2_7_8_1","first-page":"105","article-title":"Dysphonia due to unilateral nerve paralysis. 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