{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T18:39:54Z","timestamp":1776537594397,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T00:00:00Z","timestamp":1525392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Case reports of a painful variant of Hashimoto's thyroiditis exist in the literature; however, these cases have only been documented in adult patients and there are no standard treatment guidelines. The aim of this study was to describe an alternative management for Hashimoto's thyroiditis associated with medically intractable head and neck pain in the pediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was conducted in the Section of Pediatric Otolaryngology at the Cleveland Clinic. We retrospectively analyzed pediatric patients (ages 0\u201318 years) with painful thyroiditis and\/or headache who underwent total thyroidectomy from 2005 to 2014 with a clinical diagnosis of Hashimoto's thyroiditis. A thorough chart review was performed, including medical and family history, presenting symptoms, laboratory values, medical and surgical treatment strategies, operative reports, and surgical pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 0.02% of patients (5 of 305) who met the criteria of intractable head and or neck pain. All five underwent total thyroidectomy with confirmation of Hashimoto's thyroiditis on surgical pathology. Surgical treatment resulted in complete cervical pain relief and improved headaches with a minimum follow\u2010up of 36 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Hashimoto's thyroiditis is a relatively common form of autoimmune thyroiditis in pediatric patients that uncommonly results in intractable neck pain or headache. In this case series, thyroidectomy was an effective alternative treatment in the pediatric population for medical failures in chronic painful Hashimoto's thyroiditis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 128:2213\u20132217, 2018<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27099","type":"journal-article","created":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T10:27:03Z","timestamp":1525429623000},"page":"2213-2217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical management of neck pain and headache associated with pediatric hashimoto's thyroiditis"],"prefix":"10.1002","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5925-7802","authenticated-orcid":false,"given":"Paul","family":"Krakovitz","sequence":"first","affiliation":[{"name":"Head and Neck Institute, Section of Pediatric Otolaryngology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Cairns","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology University of Vermont Medical Center Burlington Vermont"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahareh Michelle","family":"Schweiger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Pediatric Endocrinology Cedars\u2010Sinai Medical Center Los Angeles California U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Burkey","sequence":"additional","affiliation":[{"name":"Head and Neck Institute, Section of Pediatric Otolaryngology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/1742-6413.131741"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-39-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.81867"},{"key":"e_1_2_6_5_1","first-page":"349756","article-title":"Surgical treatment for unexplained severe pain of the thyroid gland: report of three cases and concise review of the literature","volume":"2011","author":"Schaik J","year":"2011","journal-title":"Case Rep 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