{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:45:09Z","timestamp":1773305109103,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T00:00:00Z","timestamp":1536019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To examine the effects of dairy versus nondairy diets on self\u2010reported levels of nasopharyngeal mucus secretion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective, randomized, double\u2010blinded controlled study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010six men and 82 consecutive women over the age of 15 years attending the otolaryngology department at East and North Hertfordshire NHS Trust who reported experiencing increased levels of nasopharyngeal mucus secretions were selected for a double\u2010blinded trial of dairy versus dairy\u2010free dietary supplementation for the last 4 days of a 6\u2010day dairy\u2010free diet. Main outcome measures were comparisons of mean daily reporting of subjective levels of nasopharyngeal secretions by linear scoring (1\u2013100) and by an ordinal scale of 1 to 4. On each day, <jats:italic>t<\/jats:italic> tests were used to compare differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant reduction in the reported linear secretion score seen from day 1 to 4 in nondairy (<jats:italic>t<\/jats:italic>[53]\u2009=\u20094.39, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) and in dairy (<jats:italic>t<\/jats:italic>[53]\u2009=\u20093.94, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) arms. There was a significant increase in secretion score days 4 to 7 in the dairy arm (<jats:italic>t<\/jats:italic>[53]\u2009=\u2009\u22122.56, <jats:italic>P<\/jats:italic>\u2009=\u2009.01), and a continued but nonsignificant reduction in the nondiary arm (<jats:italic>t<\/jats:italic>[53]\u2009=\u20091.54, <jats:italic>P<\/jats:italic>\u2009=\u2009.13, with an overall significant reduction between day 1 and 7 in the nondairy arm (<jats:italic>t<\/jats:italic>[53]\u2009=\u20094.79, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.00). In the ordinal secretion scale, both dairy arm (<jats:italic>t<\/jats:italic>[53]\u2009=\u20092.754, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) and nondiary arm (<jats:italic>t<\/jats:italic>[53]\u2009=\u20095.52, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) scores decreased significantly from days 1 to 4. There was a significant decrease in scores from days 1 to 7 in the nondairy group (<jats:italic>t<\/jats:italic>[53]\u2009=\u20095.12, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this blinded trial, a dairy\u2010free diet was associated with a significant reduction in self\u2010reported levels of nasopharyngeal secretions in adults who previously complained of persistent nasopharyngeal mucus hypersecretion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>1b <jats:italic>Laryngoscope<\/jats:italic>, 129:13\u201317, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27287","type":"journal-article","created":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T10:25:01Z","timestamp":1536056701000},"page":"13-17","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of a dairy diet on nasopharyngeal mucus secretion"],"prefix":"10.1002","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4880-8821","authenticated-orcid":false,"given":"Adam","family":"Frosh","sequence":"first","affiliation":[{"name":"Department of ENT Surgery, the Department of Nursing Research Lister Hospital  Stevenage Hertfordshire SG1 4AB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of ENT Surgery, the Department of Nursing Research Lister Hospital  Stevenage Hertfordshire SG1 4AB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wellsted","sequence":"additional","affiliation":[{"name":"Centre for Health Services and Clinical research University of Hertfordshire, College Lane  Hatfield Hertfordshire UK, AL10 9AB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Stephens","sequence":"additional","affiliation":[{"name":"Department of ENT Surgery, the Department of Nursing Research Lister Hospital  Stevenage Hertfordshire SG1 4AB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"178","article-title":"The effect of gender and occupation on the contribution of dairy foods to nutrient intake in an urban population","volume":"40","author":"Baghurst KI, Syrette JA","year":"1988","journal-title":"Food Technol Aust"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.36.4.245"},{"key":"e_1_2_6_4_1","volume-title":"Baby and Child Care","author":"Spock 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