{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:34:56Z","timestamp":1777620896773,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T00:00:00Z","timestamp":1541635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institutes of Health, National Institute on Deafness and other Communicative Disorders","award":["R01 DC008153"],"award-info":[{"award-number":["R01 DC008153"]}]},{"name":"Diane M. Bless Endowed Chair, Division of Otolaryngology-Head and Neck Surgery at the University of Wisconsin-Madison"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Phonation threshold pressure (PTP), the minimum subglottal pressure (P<jats:sub>s<\/jats:sub>) required for phonation, is sensitive to changes in laryngeal biomechanics and is often elevated with pathology. Little is reported on PTP in children; challenges with task performance and measurement reliability represent barriers to routine clinical assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Pilot study evaluating PTP and P<jats:sub>s<\/jats:sub> measurement reliability in children using labial and mechanical interruption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010two subjects aged 4 to 17 years (10.7\u2009\u00b1\u20093.9 years) participated. Ten trials were performed for each method; task order was randomized. For labial interruption, subjects produced \/p\u03b1\/ five times at softest (onset PTP) and comfortable amplitude. For mechanical interruption, subjects produced a sustained \/\u03b1\/ while a balloon valve interrupted phonation five times for 250 ms each; mechanical interruption was performed with a mouthpiece and mask. PTP was recorded as the difference between P<jats:sub>s<\/jats:sub> and supraglottal pressure at phonation cessation (offset PTP). Mean PTP and P<jats:sub>s<\/jats:sub> and intrasubject coefficients of variation were compared. Correlations with age were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean PTP (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) and P<jats:sub>s<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009=\u2009.005) were higher for labial interruption. Intrasubject coefficients of variation for PTP (<jats:italic>P<\/jats:italic>\u2009=\u2009.554) and P<jats:sub>s<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009=\u2009.305) were similar across methods. Coefficient of variation was related to age for mechanical\u2010mask trials only (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.628, <jats:italic>P<\/jats:italic>\u2009=\u2009.00175).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Differences in means are likely related to differences in task and PTP hysteresis effect. Reliability is comparable with all methods; using a mouthpiece may be preferable to a mask for mechanical interruption. Measurement of PTP is noninvasive, reliable, and may be a useful adjunct in pediatric voice assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3b<\/jats:p><jats:p><jats:italic>Laryngoscope<\/jats:italic>, 129:1520\u20131526, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27418","type":"journal-article","created":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T19:47:38Z","timestamp":1541706458000},"page":"1520-1526","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Measurement reliability of phonation threshold pressure in pediatric subjects"],"prefix":"10.1002","volume":"129","author":[{"given":"Matthew R.","family":"Hoffman","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin J.","family":"Scholp","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calvin D.","family":"Hedberg","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim R.","family":"Lamb","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maia N.","family":"Braden","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Scott","family":"McMurray","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack J.","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2010Head and Neck Surgery University of Wisconsin School of Medicine and Public Health  Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24931"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2005.07.004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2013.02.001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2006.09.005"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/14015439.2011.638670"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305683"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.04.001"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.395910"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.411870"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(00)80080-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940411301001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940411301205"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.3705.1001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900607"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1044\/1058-0360(2011\/10-0066)"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.4602.138"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.388046"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80248-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210100706"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199903000-00016"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(99)80012-5"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2010.01.004"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31816e2ec7"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.414354"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.424572"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2004.07.009"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(98)80036-2"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.407365"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12213"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1044\/1058-0360(2008\/08-0017)"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2007.09.005"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1812309"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20611"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2012.09.001"},{"key":"e_1_2_6_36_1","unstructured":"Titze IR. 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