{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:54:40Z","timestamp":1782928480391,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T00:00:00Z","timestamp":1539302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>This is a retrospective study investigating the prevalence of globus pharyngeus in patients with dysphonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study examined the prevalence of globus pharyngeus in patients presenting with history of dysphonia at the American University of Beirut Medical Center Voice Center was performed. The etiology of dysphonia was categorized as organic in the presence of laryngeal pathology versus functional in the absence of any laryngeal pathology on laryngeal videostroboscopic examination. Functional dysphonia was further stratified as muscle tension dysphonia (MTD) and non\u2010MTD based on the presence or absence of supraglottic muscle tension patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The medical records of 300 patients were reviewed. Total prevalence of globus pharyngeus was 14.33%. There was a significant difference in the prevalence of globus pharyngeus between patients with organic dysphonia and patients with functional dysphonia (<jats:italic>P<\/jats:italic> &lt; .001). Out of 43 patients with globus, 41.86% had organic voice disorders versus 58.14% who had functional voice disorders. Among those with functional voice disorders, globus pharyngeus was more prevalent in patients with MTD versus non\u2010MTD patients (<jats:italic>P<\/jats:italic> = .19). Out of 25 patients with functional voice disorders and globus, 72% had MTD versus 28% who had no MTD (<jats:italic>P<\/jats:italic> = .19).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Globus pharyngeus is significantly more prevalent in patients with functional dysphonia versus patients with organic dysphonia. Moreover, in patients with functional dysphonia, the prevalence of globus was higher in those with MTD despite not reaching statistical significance. Globus pharyngeus may be either the cause or the result of laryngeal aberrant functional behavior.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 129:930\u2013934, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27493","type":"journal-article","created":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T02:44:13Z","timestamp":1539398653000},"page":"930-934","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Predictive value of globus pharyngeus in patients with functional dysphonia versus organic dysphonia"],"prefix":"10.1002","volume":"129","author":[{"given":"Abdul\u2010Latif","family":"Hamdan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Khalifee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisham","family":"Mansour","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmond","family":"Yammine","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i20.2462"},{"key":"e_1_2_6_3_1","volume-title":"A Treatise of Vapours or Hysterick Fits","author":"Purcell J","year":"1707"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100068687"},{"key":"e_1_2_6_5_1","first-page":"46","article-title":"Heartburn and globus in apparently healthy people","volume":"126","author":"Thompson WG","year":"1982","journal-title":"Can Med Assoc J"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100104384"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1982.00790590062017"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199510000-00019"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1540\/jsmr.50.66"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajot.2001.24823"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.02.003"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940511400401"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12103"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20553"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816657013"},{"key":"e_1_2_6_16_1","first-page":"531","article-title":"The study of allergic skin test in patients with globus pharyngeus: a preliminary report","volume":"92","author":"Jaruchinda P","year":"2009","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90386-Y"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200205000-00019"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01145.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.08.025"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.7.827"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2004.03.007"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.109935"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1991.101.s53.1"},{"key":"e_1_2_6_25_1","first-page":"302","article-title":"Muscular tension dysphonia","volume":"12","author":"Morrison MD","year":"1983","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01303162"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(95)71614-0"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00097-8"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200108000-00001"},{"key":"e_1_2_6_30_1","first-page":"637","volume-title":"Diagnosis and Treatment of Voice Disorders","author":"Rubin JS","year":"2006"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.02.019"},{"key":"e_1_2_6_32_1","first-page":"161","article-title":"Correlation between female sex and allergy was significant in patients presenting with dysphonia","volume":"31","author":"Lauriello M","year":"2011","journal-title":"Acta Otorhinolaryngologica Italica"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815607850"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2012.10.001"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.12.1534"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31815ed13a"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2006.08.007"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.3109\/14015439709075313"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(96)00024-4"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6815-10-5"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215110001866"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.27493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.27493","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T02:10:24Z","timestamp":1694398224000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.27493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,12]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1002\/lary.27493"],"URL":"https:\/\/doi.org\/10.1002\/lary.27493","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,12]]},"assertion":[{"value":"2018-07-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}