{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:43:10Z","timestamp":1787748190892,"version":"build-2784847793"},"reference-count":55,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T00:00:00Z","timestamp":1545955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Seoul National University Boramae Medical Center"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Recently, the endoscope has been increasingly introduced for middle\u2010ear surgery. To evaluate the postoperative outcomes of endoscopic ear surgery (EES) in pediatric patients, we did a qualitative analysis with a systematic review and quantitative analysis with meta\u2010analysis of available literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Studies reporting the comparative surgical outcomes of EES in pediatric patients were systematically reviewed by searching the MEDLINE, PubMed, and Embase databases from database inception through 2017. The selected articles included clinical studies conducted with at least 30 subjects and at least one postoperative parameter, including residual or recurrent cholesteatoma and graft success in tympanoplasty. Two investigators independently reviewed all studies and extracted the data using a standardized form. A meta\u2010analysis was performed using a random\u2010effects model and qualitative review was performed on the smaller studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten studies were identified as appropriate for quantitative meta\u2010analysis and 19 studies for qualitative analysis. In the meta\u2010analysis, residual or recurrence rate of cholesteatoma was significantly lower in the EES group than in the microscopic ear surgery (MES) group (odds ratio [OR]: 0.56, 95% confidence interval [CI]: 0.38\u20100.84, <jats:italic>P<\/jats:italic>\u2009=\u2009.005). The graft success rate of tympanoplasty was not statistically different between EES and MES groups (OR: 0.72, 95% CI: 0.41\u20101.26, <jats:italic>P<\/jats:italic>\u2009=\u2009.249). In the qualitative analysis, most of the studies reported similar audiological outcomes after tympanoplasty and success rate of cholesteatoma removal between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It appears that EES reduces the risk of residual cholesteatoma in children and that the success of perforation closure is equivalent to MES.<\/jats:p><jats:p><jats:italic>Laryngoscope<\/jats:italic>, 129:1444\u20131452, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27556","type":"journal-article","created":{"date-parts":[[2018,12,29]],"date-time":"2018-12-29T02:58:55Z","timestamp":1546052335000},"page":"1444-1452","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Comparison of endoscopic and microscopic ear surgery in pediatric patients: A meta\u2010analysis"],"prefix":"10.1002","volume":"129","author":[{"given":"Sang\u2010Yoon","family":"Han","sequence":"first","affiliation":[{"name":"the Department of Otorhinolaryngology\u2013Head and Neck Surgery Seoul National University Boramae Medical Center, Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1590-8559","authenticated-orcid":false,"given":"Doh Young","family":"Lee","sequence":"additional","affiliation":[{"name":"the Department of Otorhinolaryngology\u2013Head and Neck Surgery Seoul National University Boramae Medical Center, Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juyong","family":"Chung","sequence":"additional","affiliation":[{"name":"the Department of Otolaryngology\u2013Head and Neck Surgery Wonkwang University School of Medicine  Iksan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7328-5068","authenticated-orcid":false,"given":"Young Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"the Department of Otorhinolaryngology\u2013Head and Neck Surgery Seoul National University Boramae Medical Center, Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25048"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182096b39"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2016.00080"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.04.013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-016-0970-8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-010-0007-7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200209000-00004"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.03.017"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2017.01.001"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_6_13_1","first-page":"133","article-title":"Endoscopic ear surgery for pediatric cholesteatoma resection","volume":"155","author":"Basonbul RA","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817729136"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25410"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26654"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816631941"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26568"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000948"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.12.008"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.08.025"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2016.05.005"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.0601"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.02.017"},{"key":"e_1_2_6_25_1","first-page":"150","article-title":"Permeatal totally endoscopic ear surgery for congenital cholesteatoma in children","volume":"157","author":"D'Eredita R","year":"2017","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800913"},{"key":"e_1_2_6_27_1","first-page":"252","article-title":"The application of total endoscopic ear surgery in pediatric patients","volume":"155","author":"Huang TC","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_28_1","first-page":"122","article-title":"Endoscopic management of congenital ossicular fixation","volume":"153","author":"Isaacson B","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_29_1","first-page":"136","article-title":"Results of pediatric endoscopic and endoscopically assisted tympanoplasty","volume":"3","author":"Isaacson G","year":"2017","journal-title":"World J Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.10.019"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812451438a208"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000857"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.03.039"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.06.006"},{"key":"e_1_2_6_35_1","first-page":"P255","article-title":"Endoscopic ear surgery for pediatric congenital cholesteatoma","volume":"155","author":"Huang TC","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-015-0351-6"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890080038007"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815622441"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001154"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.9.1009"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346140"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1258\/0022215021911211"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100142707"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24144"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2016.05.012"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000510"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2490-4"},{"key":"e_1_2_6_48_1","first-page":"305","article-title":"Total endoscopic approach in glomus tympanicum surgery","volume":"29","author":"Daneshi A","year":"2017","journal-title":"Iran J Otorhinolaryngol"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001320"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-016-0251-6"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2015.12.014"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25634"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-015-0916-6"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25760"},{"key":"e_1_2_6_55_1","first-page":"153","article-title":"Results of endoscopic middle ear surgery for cholesteatoma treatment: a systematic review","volume":"34","author":"Presutti L","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25048"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.27556","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27556","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.27556","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27556","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T13:26:14Z","timestamp":1694352374000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.27556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,28]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1002\/lary.27556"],"URL":"https:\/\/doi.org\/10.1002\/lary.27556","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,28]]},"assertion":[{"value":"2018-03-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}