{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:26:03Z","timestamp":1790184363770,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,11]]},"abstract":"\n Objectives\/Hypothesis<\/jats:title>\n Compare surgical and audiometric outcomes following canal wall reconstruction (CWR) tympanomastoidectomy used as a primary versus secondary approach for treating cholesteatoma.<\/jats:p>\n <\/jats:sec>\n \n Study Design<\/jats:title>\n Retrospective.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Patients treated for primary\/secondary cholesteatoma from 2006 to 2017 via CWR were included if they had preoperative\/postoperative audiograms, detailed operative note(s), and >12 months\u2019 follow\u2010up. Patients were stratified by previous surgical history into two groups: primary CWR group (PG) and secondary CWR group (SG). Surgical outcomes measured were prevalence of recidivistic cholesteatoma, canal cholesteatoma, revision rate, and canal wall down (CWD) conversion rates. Secondary outcomes were prevalence of infection, external canal adhesions\/stenoses, and retractions. Audiometric outcomes included change in pure\u2010tone average and air\u2010bone gap.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We stratified 45 patients\/ears into the PG and 26 into the SG. The groups did not significantly differ in age, sex, or smoking status. Overall, median follow\u2010up was 35 months. SG patients had higher rates of cholesteatoma detected at staged surgery than did PG patients (\n P<\/jats:italic>\n \u2009=\u2009.04). However, these patients exhibited lower rates of open revision surgery (4% vs.13%) and a significant improvement in air\u2010bone gap (\n P<\/jats:italic>\n \u2009=\u2009.004). Three PG patients (7%) required conversion to CWD versus zero SG patients. Secondary outcomes were similar. Patients who underwent delayed staging >12 months from CWR had increased rates of recidivism and canal adhesion\/stenosis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n CWR was effective for treating cholesteatoma as both a primary and secondary surgical approach. SG patients experienced higher rates of recidivism and secondary canal cholesteatoma. PG patients had higher rates of revision surgery. Staging of ears undergoing CWR is important regardless of prior surgical history.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n \n 4\n Laryngoscope<\/jats:italic>\n , 129:2580\u20132587, 2019\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lary.27558","type":"journal-article","created":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T21:31:18Z","timestamp":1552944678000},"page":"2580-2587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Canal reconstruction mastoidectomy: Outcomes comparison following primary versus secondary surgery"],"prefix":"10.1002","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-1584","authenticated-orcid":false,"given":"Shawn M.","family":"Stevens","sequence":"first","affiliation":[{"name":"Arizona Otolaryngology Consultants and Barrow Neurological Institute Phoenix Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe A.","family":"Walters","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Cincinnati College of Medicine Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara","family":"Babo","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Cincinnati College of Medicine Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nithin","family":"Peddireddy","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Cincinnati College of Medicine Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kareem O.","family":"Tawfik","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi N.","family":"Samy","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199807000-00005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200303000-00010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600405"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198408000-00006"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24202"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116000013"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(99)00071-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488709128279"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1978.tb00744.x"},{"key":"e_1_2_6_11_1","first-page":"534","article-title":"The 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Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.27558","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T01:49:35Z","timestamp":1694224175000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.27558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,18]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1002\/lary.27558"],"URL":"https:\/\/doi.org\/10.1002\/lary.27558","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,18]]},"assertion":[{"value":"2018-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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