{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:34:48Z","timestamp":1782513288154,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T00:00:00Z","timestamp":1545955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the clinical characteristics of patients presenting with a new diagnosis of otosyphilis over the past 10 years in a large, urban, safety\u2010net hospital affiliated with a large county sexually transmitted disease clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective case series. A chart review was performed of all patients who presented to an adult otolaryngology clinic with a new diagnosis of syphilis and hearing loss from January 2008 to December 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients met the criteria for \u201csuspected\u201d or \u201clikely\u201d otosyphilis based on Centers for Disease Control and Prevention definitions. The average age was 48 years (range 19\u201359). All were male. Nine (75%) were men who have sex with men. Eight (67%) were positive for human immunodeficiency virus. One (8%) presented with primary, nine (75%) with secondary, and two (17%) with early latent syphilis. Seven (58%) presented with bilateral audiogram\u2010confirmed hearing loss, two (17%) with unilateral hearing loss, and three (25%) with suspected hearing loss based on fluctuating symptoms. Nine (75%) presented with tinnitus and two (17%) with vertigo. The median duration of otologic symptoms prior to presentation was 2 weeks (range: 0\u201316 weeks). All presented within the last 2 years surveyed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We have seen an increase in the number of otosyphilis cases in our clinic. We suspect otosyphilis may be underdiagnosed and emphasize the importance of screening for syphilis in patients with new audiologic symptoms of vertigo, tinnitus, or hearing loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4<\/jats:p><jats:p><jats:italic>Laryngoscope<\/jats:italic>, 129:1680\u20131684, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27635","type":"journal-article","created":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T10:03:56Z","timestamp":1545991436000},"page":"1680-1684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Otosyphilis: Resurgence of an Old Disease"],"prefix":"10.1002","volume":"129","author":[{"given":"Hailey","family":"Theeuwen","sequence":"first","affiliation":[{"name":"University of Washington School of Medicine  Seattle Washington U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Whipple","sequence":"additional","affiliation":[{"name":"University of Washington School of Medicine  Seattle Washington U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Harborview Medical Center University of Washington School of Medicine  Seattle Washington U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie R.","family":"Litvack","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Harborview Medical Center University of Washington School of Medicine  Seattle Washington U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,28]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"2001","volume-title":"Sexually Transmitted Disease Surveillance 2000, 2008\u20132016","author":"Centers for Disease Control and Prevention"},{"key":"e_1_2_6_3_1","unstructured":"Seattle and King County Quarterly STD Report 4th Quarter 2016.King County STD Epidemiology Reports.https:\/\/www.kingcounty.gov\/~\/media\/depts\/health\/communicable\u2010diseases\/documents\/hivstd\/STD\u2010Report\u20104Q\u20102017.ashx?la=en. 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