{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:08:03Z","timestamp":1793383683517,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,12,27]],"date-time":"2018-12-27T00:00:00Z","timestamp":1545868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001855"],"award-info":[{"award-number":["UL1TR001855"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000130"],"award-info":[{"award-number":["UL1TR000130"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the association between findings of blinded reviews of preoperative drug\u2010induced sleep endoscopy (DISE) examinations using the VOTE Classification and obstructive sleep apnea (OSA) surgical outcomes in a large multicenter, international cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective, multi\u2010center cohort study of adults without tonsillar hypertrophy who underwent pharyngeal surgery for OSA. The study included only participants without enlarged tonsils. Four independent reviewers performed blinded review of preoperative DISE videos using the VOTE Classification system and scoring of a primary structure contributing to airway obstruction. DISE findings were examined for an association with surgical outcomes with univariate analyses and multiple regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred seventy\u2010five study participants were included from 14 centers. Mean age was 51.4\u2009\u00b1\u200911.8 years, and body mass index was 30.1\u2009\u00b1\u20095.2\u2009kg\/m<jats:sup>2<\/jats:sup>. There was moderate interrater reliability (kappa\u2009=\u20090.40\u20130.60) for DISE findings. Oropharyngeal lateral wall\u2010related obstruction was associated with poorer surgical outcomes (adjusted odds ratio (AOR) 0.51; 95% CI 0.27, 0.93). Complete tongue\u2010related obstruction was associated with a lower odds of surgical response in moderate to severe OSA (AOR 0.52; 95% CI 0.28, 0.98), with findings that were similar but not statistically significant in other analyses. Surgical outcomes were not clearly associated with the degree and configuration of velum\u2010related obstruction or the degree of epiglottis\u2010related obstruction. Surgical response was associated with tonsil size and body mass index (inversely).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DISE findings concerning the oropharyngeal lateral walls and tongue may be the most important findings of this evaluation technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2B <jats:italic>Laryngoscope<\/jats:italic>, 129:761\u2013770, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27655","type":"journal-article","created":{"date-parts":[[2018,12,27]],"date-time":"2018-12-27T09:39:15Z","timestamp":1545903555000},"page":"761-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":120,"title":["Drug\u2010Induced Sleep Endoscopy and Surgical Outcomes: A Multicenter Cohort Study"],"prefix":"10.1002","volume":"129","author":[{"given":"Katherine K.","family":"Green","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Colorado School of Medicine  Denver Colorado U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Kent","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Vanderbilt University Medical Center  Nashville Tennessee U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"D'Agostino","sequence":"additional","affiliation":[{"name":"Southern New England Ear, Nose and Throat Group  Middlesex Connecticut USA"},{"name":"Department of Surgery Yale University School of Medicine  New Haven Connecticut U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul T.","family":"Hoff","sequence":"additional","affiliation":[{"name":"University of Michigan Department of Otolaryngology\u2013Head and Neck Surgery  Ann Arbor Michigan U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho\u2010Sheng","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Wayne State University School of Medicine  Detroit Michigan U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan J.","family":"Soose","sequence":"additional","affiliation":[{"name":"UPMC Department of Otolaryngology Head and Neck Surgery University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Boyd Gillespie","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Tennessee Memphis  Memphis Tennessee U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8247-1663","authenticated-orcid":false,"given":"Kathleen L.","family":"Yaremchuk","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Henry Ford Health System  Detroit Michigan U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0849-5901","authenticated-orcid":false,"given":"Marina","family":"Carrasco\u2010Llatas","sequence":"additional","affiliation":[{"name":"ENT department, Hospital Universitario Dr. Peset  Valencia Spainc"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2396-2926","authenticated-orcid":false,"given":"B.","family":"Tucker Woodson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Communication Sciences, Medical College of Wisconsi  Milwaukee Wisconsin U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer","family":"Jacobowitz","sequence":"additional","affiliation":[{"name":"ENT and Allergy Associates  New York New York U.S.A."},{"name":"Department of Otolaryngology The Mount Sinai Hospital  New York New York U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica R.","family":"Thaler","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology: Head and Neck Surgery Perelman School of Medicine of the University of Pennsylvania  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E.","family":"Barrera","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Uniformed Services University  Washington D.C. U.S.A."},{"name":"Endormir Sleep and Sinus Institute  San Antonio Texas U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robson","family":"Capasso","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University School of Medicine  Stanford California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley Yung","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University School of Medicine  Stanford California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Hsia","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, University of Minnesota Medical School  Minneapolis Minnesota U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daljit","family":"Mann","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center Department of Otolaryngology\u2013Head &amp; Neck Surgery  Oklahoma City Oklahoma U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taha S.","family":"Meraj","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Wayne State University School of Medicine  Detroit Michigan U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Waxman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Wayne State University School of Medicine  Detroit Michigan U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3808-4521","authenticated-orcid":false,"given":"Eric J.","family":"Kezirian","sequence":"additional","affiliation":[{"name":"USC Caruso Department of Otolaryngology\u2013Head &amp; Neck Surgery Keck School of Medicine of the University of Southern California  Los Angeles California U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1991.tb02103.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181a7ec68"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2004.00864.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/0365523031000055"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23462"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22474"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26255"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-014-1107-5"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6756"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)36806-7"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.126477"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-011-1633-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.2.156"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.2.206"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815576719"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00020"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.03.014"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20634"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199303000-00006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00059414"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2015.01.028"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200403000-00013"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26038"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815575721"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817698671"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-013-0875-7"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcp.0000245706.77064.51"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.11.001"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.27655","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.27655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T13:08:22Z","timestamp":1694696902000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.27655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,27]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1002\/lary.27655"],"URL":"https:\/\/doi.org\/10.1002\/lary.27655","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,27]]},"assertion":[{"value":"2018-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}