{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:03:22Z","timestamp":1783389802423,"version":"3.54.6"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T00:00:00Z","timestamp":1545609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 DC005356"],"award-info":[{"award-number":["T32 DC005356"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Peritonsillar abscess (PTA) is a common infectious complication of pharyngeal infection managed by otolaryngologists and emergency room physicians. <jats:italic>Streptococcus<\/jats:italic> and <jats:italic>Fusobacterium<\/jats:italic> (e.g., <jats:italic>Fusobacterium necrophorum, FN)<\/jats:italic> species are commonly isolated pathogens. The aim of this study was to determine the implication of culture results on abscess recurrence following drainage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010institution retrospective review of patients treated at the University of Michigan between 2000 and 2017. Demographic and clinical outcome data were analyzed, including treatment details, culture data, and recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred fifty\u2010six of the 990 patients in our study developed recurrence of their abscess (16%). The age ranges most susceptible to recurrence included adolescent (22.9%) and young adult groups (17.1%). Recurrent patients were more likely to have experienced acute progression of symptoms (79% vs. 71%, <jats:italic>P<\/jats:italic>\u2009=\u20090.03), trismus (67% vs. 55%, <jats:italic>P<\/jats:italic>\u2009=\u20090.006), voice changes (65% vs. 57%, <jats:italic>P<\/jats:italic>\u2009=\u20090.04), and dysphagia (72% vs. 61%, <jats:italic>P<\/jats:italic>\u2009=\u20090.01) compared to nonrecurrent patients. They were also more likely to have clinical lymphadenopathy noted on initial examination (67% vs. 56%, <jats:italic>P<\/jats:italic>\u2009=\u20090.009). Culture data was sent for 852 patients (86%). The presence of <jats:italic>FN<\/jats:italic> was significantly more prevalent in the recurrent group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a high observed prevalence of <jats:italic>FN<\/jats:italic> species within PTA aspirates in the recurrent PTA population. PTA aspirate should be sent for anaerobic growth to screen for <jats:italic>Fusobacterium<\/jats:italic> species. In addition, follow\u2010up and lower threshold for subsequent tonsillectomy should be considered in this at\u2010risk group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3<\/jats:p><jats:p><jats:italic>Laryngoscope<\/jats:italic>, 129:1567\u20131571, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27675","type":"journal-article","created":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T14:13:02Z","timestamp":1545660782000},"page":"1567-1571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Implication of <i>Fusobacterium necrophorum<\/i> in recurrence of peritonsillar abscess"],"prefix":"10.1002","volume":"129","author":[{"given":"S. Ahmed","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery  Ann Arbor Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin J.","family":"Kovatch","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery  Ann Arbor Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh","family":"Smith","sequence":"additional","affiliation":[{"name":"School of Medicine University of Michigan  Ann Arbor Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"Bellile","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Michigan Medicine  Ann Arbor Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Hanks","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery  Ann Arbor Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul T.","family":"Hoff","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; 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