{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:25:11Z","timestamp":1760217911411,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Clinical outcomes for type I Gore\u2010Tex thyroplasty (GMT) for nonparalytic glottic incompetence (GI) have been reported in the literature. Given differences in male and female laryngeal anatomy, sex\u2010based outcomes should also be evaluated. We endeavored to evaluate sex\u2010specific post\u2010GMT voice outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective review of patients undergoing GMT for nonparalytic GI. Multidimensional voice outcome measures including voice\u2010related quality of life (VRQOL), Glottal Function Index (GFI), and grade\/roughness\/breathiness\/asthenia\/strain (GRBAS) were analyzed at postoperative time frames: 0 to 3 months, 3 to 9 months, and 9 to 18 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010five subjects (43 females, 42 males) with mean age 53.5 undergoing GMT for nonparalytic GI from 2005 to 2017 met inclusion criteria. Etiologies included vocal fold hypomobility (N = 36, 42%), paresis (N = 18, 21%), vocal fold atrophy (N = 17, 20%), and scarring (N = 14, 17%). Females had significantly greater improvement on VRQOL at 0 to 3 months and 9 to 18 months timeframes compared to males, with mean change in VRQOL: 41.3 versus 22.4 (<jats:italic>P<\/jats:italic> = 0.0002) and 42.5 versus 20.8 (<jats:italic>P<\/jats:italic> = 0.002), respectively. Similarly, women had significantly greater improvement in GFI at 0 to 3 months follow\u2010up (mean difference \u2212 10.8 vs. \u22124.9, respectively, <jats:italic>P<\/jats:italic> = 0.0002). There was no statistically significant sex difference in GRBAS at any follow\u2010up interval.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Following GMT, females had greater improvement in patient\u2010reported voice outcomes in the early postoperative period. No significant difference between sexes was noted in perceptual measures (GRBAS). Sex\u2010specific outcomes should be evaluated for clinical interventions to improve specificity of preoperative counseling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 129:2543\u20132548, 2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27770","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T10:00:27Z","timestamp":1547200827000},"page":"2543-2548","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sex\u2010based outcomes in type I thyroplasty for nonparalytic glottic incompetence"],"prefix":"10.1002","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2357-7294","authenticated-orcid":false,"given":"Zainab","family":"Farzal","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis J.","family":"Overton","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas R.","family":"Farquhar","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3678-3989","authenticated-orcid":false,"given":"Elizabeth D.","family":"Stephenson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupali N.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Buckmire","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,10]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"7","article-title":"Long\u2010term results of different treatment modalities for glottic insufficiency","volume":"29","author":"Dursun G","year":"2008","journal-title":"Am J Otolaryngol Head Neck Med 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