{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:59:08Z","timestamp":1777949948547,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T00:00:00Z","timestamp":1554595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Transoral surgery (TOS) for oropharyngeal carcinoma (OPC) is steadily becoming more routine. Expected posttreatment swallow function is a critical consideration for preoperative counseling. The objective of this study was to identify predictors of swallow dysfunction following TOS for advanced tumor (T)\u2010stage (T3\u2010T4) OPC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review from 1997 to 2016 at a single institution was performed. Eighty\u2010two patients who underwent primary transoral resection of locally advanced OPCs with at least 1\u2009year of postoperative follow\u2010up were included.<\/jats:p><jats:p>The primary outcome measure was swallow function, as measured by the Functional Outcomes Swallowing Scale (FOSS) at 1\u2009year postoperatively. Operative reports were reviewed, and the extent of resection and type of reconstruction were documented. Conjunctive consolidation was then performed to incorporate multiple variables and their impact on swallow function into a clinically meaningful classification system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010six patients (68%) had acceptable swallowing at 1\u2009year. T4 tumor stage and receipt of adjuvant chemoradiation therapy (CRT) were strongly associated with poor swallowing but did not reach statistical significance. Only base of tongue (BOT) resection \u226550% (odds ratio [OR] 3.19, 95% confidence interval [CI] 1.21\u20138.43) and older age (OR 1.06, 95% CI 1.00\u20131.12) were significantly associated. Utilizing T\u2010stage, adjuvant CRT, and BOT resection, a conjunctive consolidation was performed to develop a classification system for swallow dysfunction at 1\u2009year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study provides risk stratification for swallow function at 1\u2009year following primary transoral resection of locally advanced OPCs. BOT resection \u226550%, especially when coupled with T4 tumor stage or adjuvant CRT, was associated with poor long\u2010term swallow outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 130:94\u2013100, 2020<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.27856","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T06:25:58Z","timestamp":1554704758000},"page":"94-100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Predictors of swallow function after transoral surgery for locally advanced oropharyngeal cancer"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4241-4821","authenticated-orcid":false,"given":"Jennifer H.","family":"Gross","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Washington University School of Medicine  Saint Louis Missouri 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