{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:41:56Z","timestamp":1767706916283,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To examine if there has been a reduction in premature mortality due to head and neck cancers and their subtypes in the Canadian population between 1980 and 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective database review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Mortality data for head and neck cancers were obtained from the World Health Organization's mortality database. Years of life lost (YLL) was calculated according to Canadian life tables. A new measure, average lifespan shortened (ALSS), was calculated as a ratio of YLL over the expected lifespan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the period of interest, decreases in age standardized rates of death adjusted to the World Standard Population were observed mainly among men. The adjusted YLL rates remained unchanged with respect to oral cancers in women, but slightly decreased for oral cancers in men and for laryngeal cancers in both sexes. Our new measure of ALSS showed that in 1980, patients with oral cancers lost an average of 20% of their lifespan, whereas in 2010, men and women still lost approximately 20% and 18%, respectively. Patients with laryngeal cancers lost 18% of their lifespan in both sexes in 1980 and 17% in 2010. The ALSS subanalysis showed that the largest gain of lifespan was observed for cancers of the hypopharynx in men and for cancers of the floor of mouth and nasopharynx in women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There appears to be modest improvements in premature mortality due to head and neck cancers in Canada over a 30\u2010year period, with the exception of oral cancers in men. Changes in premature mortality varied slightly by cancer subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA <jats:italic>Laryngoscope<\/jats:italic>, 130:911\u2013917, 2020<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.28024","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T15:55:39Z","timestamp":1556207739000},"page":"911-917","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Premature deaths due to head and neck cancers in canada: A nationwide analysis from 1980 to 2010"],"prefix":"10.1002","volume":"130","author":[{"given":"Kayla Marie","family":"Atchison","sequence":"first","affiliation":[{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9442-2930","authenticated-orcid":false,"given":"Truong\u2010Minh","family":"Pham","sequence":"additional","affiliation":[{"name":"Surveillance and Reporting Cancer Control Alberta, Alberta Health Services  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khokan C.","family":"Sikdar","sequence":"additional","affiliation":[{"name":"Surveillance and Reporting Public Health Surveillance and Infrastructure Population, Public and Indigenous, Alberta Health Services  Calgary Alberta Canada"},{"name":"Community Health Sciences Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee\u2010Anne","family":"Weeks","sequence":"additional","affiliation":[{"name":"Surveillance and Reporting Cancer Control Alberta, Alberta Health Services  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony Paul Vytautas","family":"Karosas","sequence":"additional","affiliation":[{"name":"Surveillance and Reporting Cancer Control Alberta, Alberta Health Services  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aynharan","family":"Sinnarajah","sequence":"additional","affiliation":[{"name":"Community Health Sciences Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"},{"name":"Department of Family Medicine Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"},{"name":"Department of Oncology Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph C.","family":"Dort","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Otolaryngology\u2013Head and Neck Surgery Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winson Y.","family":"Cheung","sequence":"additional","affiliation":[{"name":"Department of Oncology Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Shack","sequence":"additional","affiliation":[{"name":"Surveillance and Reporting Cancer Control Alberta, Alberta Health Services  Calgary Alberta Canada"},{"name":"Community Health Sciences Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"},{"name":"Department of Oncology Cumming School of Medicine, University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60728-X"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djk179"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-0347"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70017-6"},{"key":"e_1_2_7_6_1","unstructured":"Canadian Cancer Society. 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