{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:30:30Z","timestamp":1747150230769,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:00:00Z","timestamp":1565222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To investigate the natural progression of hearing loss in patients with high\u2010frequency hearing loss whose audiograms met the criteria for a hybrid cochlear implant (CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective database review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively identified patients who met the criteria for a hybrid CI from our audiometric database. We also recorded the etiology of hearing loss in each patient and excluded patients with retrocochlear etiologies, those age\u2009&lt;6 years, duration of observation &lt;1 year, or those with a mixed or conductive hearing loss. We calculated the pre\u2010CI progression of residual low\u2010frequency (LF) hearing level in decibels per year and investigated the risk factor of the progression of hearing loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,083 ears of 944 patients were included in this study. The average rate of hearing loss progression for all etiologies was 1.70\u2009\u00b1\u20090.10 dB\/yr at an average of 250 Hz, 500 Hz, and 1 kHz in the affected ear(s). The progression of hearing loss was 5.0\u2009\u00b1\u20090.93 dB\/yr in patients with Meniere's disease and 3.5\u2009\u00b1\u20090.76 dB\/yr in those with autoimmune disease, both of which were significantly faster than progression rates in other etiologies. In patients with idiopathic, genetic\/hereditary, and congenital hearing loss, the progression of hearing loss was 1.46\u2009\u00b1\u20090.10 dB\/yr. Patients with steeply sloping hearing loss experienced significantly faster progression in the ipsilateral ear compared to patients with another audiometric type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It is suggested that Meniere's disease, autoimmune\u2010mediated inner ear disease, and steeply sloping hearing loss in the ipsilateral ear are risk factors for faster progression of residual LF hearing level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4<\/jats:p><jats:p><jats:italic>Laryngoscope<\/jats:italic>, 130:1299\u20131303, 2020<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.28217","type":"journal-article","created":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T13:59:12Z","timestamp":1565272752000},"page":"1299-1303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The natural progression of low\u2010frequency hearing loss in patients who meet hybrid implant system candidacy criteria"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9057-0784","authenticated-orcid":false,"given":"Masahiro","family":"Okada","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Ehime University School of Medicine  Toon Japan"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear and Harvard University  Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Quinkert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Massachusetts Eye and Ear and Harvard University  Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin H.","family":"Franck","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Massachusetts Eye and Ear and Harvard University  Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9963-469X","authenticated-orcid":false,"given":"D. Bradley","family":"Welling","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Massachusetts Eye and Ear and Harvard University  Boston Massachusetts U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26669"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25572"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2016.1252061"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001517"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480500488917"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22142"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342821"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1044\/1092-4388(2006\/077)"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001573"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2015.08.018"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000754"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20787"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5867\/medwave.2017.6863"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/16513860903565214"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/isbn.978-3-318-00870-8"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.28217","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.28217","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.28217","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.28217","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T16:07:54Z","timestamp":1694016474000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.28217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,8]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1002\/lary.28217"],"URL":"https:\/\/doi.org\/10.1002\/lary.28217","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"type":"print","value":"0023-852X"},{"type":"electronic","value":"1531-4995"}],"subject":[],"published":{"date-parts":[[2019,8,8]]},"assertion":[{"value":"2019-04-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}