{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T19:14:26Z","timestamp":1789067666882,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T00:00:00Z","timestamp":1573430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002537"],"award-info":[{"award-number":["UL1TR002537"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["P50 DC000242"],"award-info":[{"award-number":["P50 DC000242"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the long\u2010term audiometric outcomes, sound localization abilities, binaural benefits, and tinnitus assessment of subjects with cochlear implant (CI) after a diagnosis of unilateral severe\u2010to\u2010profound hearing loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The study group consisted of 60 (mean age 52\u2009years, range 19\u201384) subjects with profound hearing loss in one ear and normal to near\u2010normal hearing in the other ear who underwent CI. Data analysis included pre\u2010 and postoperative Consonant\u2010Nucleus\u2010Consonant (CNC) Word scores, AzBio Sentence scores, pure tone thresholds, sound localization, and Iowa Tinnitus Handicap Questionnaire scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Preoperative average duration of deafness was 3.69\u2009years (standard deviation 4.31), with an average follow\u2010up time of 37.9 months (range 1\u201387). CNC and AzBio scores significantly improved (both <jats:italic>P<\/jats:italic> &lt;\u20090.001) postoperatively among the entire cohort, and there was much heterogeneity in outcomes with respect to deafness etiology subgroup analysis. Sound localization abilities tended to improve longitudinally in the entire cohort. Binaural benefits using an adaptive Hearing in Noise Test test showed a significant (<jats:italic>P<\/jats:italic> &lt;\u20090.001) improvement with head shadow effect. Utilizing the Iowa Tinnitus Handicap Questionnaire, there was significant improvement in social, physical, and emotional well\u2010being (<jats:italic>P<\/jats:italic> =\u20090.011), along with hearing abilities (<jats:italic>P<\/jats:italic> =\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This case series is the largest cohort of CI SSD subjects to date and systematically analyzes their functional outcomes. Subjects have meaningful improvement in word understanding, and sound localization tends to gradually improve over time. Binaural benefit analysis showed significant improvement with head shadow effect, which likely provides ease of listening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 130:1805\u20131811, 2020<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.28358","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T18:10:57Z","timestamp":1573495857000},"page":"1805-1811","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Long\u2010term audiologic outcomes after cochlear implantation for single\u2010sided deafness"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1624-7422","authenticated-orcid":false,"given":"Christopher Blake","family":"Sullivan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaid","family":"Al\u2010Qurayshi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7825-8162","authenticated-orcid":false,"given":"Vivian","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7839-2073","authenticated-orcid":false,"given":"Camille","family":"Dunn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce J.","family":"Gantz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."},{"name":"Department of Neurosurgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6884-4897","authenticated-orcid":false,"given":"Marlan R.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa U.S.A."},{"name":"Department of Neurosurgery University of Iowa Hospitals and Clinics  Iowa City Iowa 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