{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:09:51Z","timestamp":1792130991216,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T00:00:00Z","timestamp":1604793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K23AG057832"],"award-info":[{"award-number":["K23AG057832"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["L30AG060513"],"award-info":[{"award-number":["L30AG060513"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The progression and asymmetry of age\u2010related hearing loss has not been well characterized in those 80\u2009years of age and older because public datasets mask upper extremes of age to protect anonymity. We aim to characterize the progression, severity, and asymmetry of hearing loss in those 80\u2009years of age and older using a representative, national database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cross\u2010sectional, multicentered U.S. epidemiologic analysis using the National Health and Nutrition Examination Survey (NHANES) 2005 to 2006, 2009 to 2010, and 2011 to 2012\u2009cycles. Subjects included noninstitutionalized, civilian adults aged 80\u2009years and older (n = 621). Federal security clearance was granted to access publicly restricted age data. Outcome measures included pure\u2010tone average (PTA) air conduction thresholds and the 4\u2010frequency PTA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six hundred and twenty\u2010one subjects were 80\u2009years old or older (mean = 84.2\u2009years, range = 80\u2013104\u2009years), representing 10,600,197 Americans. The average PTA was 38.9\u2009dB (95% confidence interval [CI] = 37.8, 40.0). Hearing loss exhibited constant acceleration across the adult lifespan at a rate of 0.0052\u2009dB\/year<jats:sup>2<\/jats:sup> (95% CI = 0.0049, 0.0055). This model predicted mean PTA within 2\u2009dB of accuracy for most ages between 20 and 100\u2009years. From age 80\u2009years to approximately 100\u2009years, the average PTA difference between the better and worse ear was 6.75\u2009dB (95% CI = 5.8, 7.1). This asymmetry was relatively constant (i.e., nonsignificant linear regression coefficient of asymmetry over age = 0.07 [95% CI = \u22120.01, 0.2]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hearing loss steadily and predictably accelerates across the adult lifespan to at least age 100\u2009years, becoming near universal. These population\u2010level statistics will guide treatment and policy recommendations for hearing health in the older old.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 131:879\u2013884, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.28971","type":"journal-article","created":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T15:00:26Z","timestamp":1604847626000},"page":"879-884","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Modeling Hearing Loss Progression and Asymmetry in the Older Old: A National <scp>Population\u2010Based<\/scp> Study"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3120-6194","authenticated-orcid":false,"given":"Rahul K.","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Columbia University Vagelos College of Physicians and Surgeons, NewYork\u2010Presbyterian\/Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Lalwani","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Columbia University Vagelos College of Physicians and Surgeons, NewYork\u2010Presbyterian\/Columbia University Irving Medical Center  New York NY USA"},{"name":"Department of Mechanical Engineering The Fu Foundation School of Engineering and Applied Science  New York City New York U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin S.","family":"Golub","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Columbia University Vagelos College of Physicians and Surgeons, NewYork\u2010Presbyterian\/Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2016.303299"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.1408"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.1868"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glz119"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2016.03.005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2019.3375"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2010.362"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14848"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000313"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.3270"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0898264315614570"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14075"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.728"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2017.07.021"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31363-6"},{"key":"e_1_2_6_17_1","unstructured":"US Department of Commerce Economics and Statistics Administration US Census Bureau. 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