{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:56:57Z","timestamp":1780361817046,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID\u201019).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective non controlled study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixteen COVID\u201019 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22\u2010item Sino\u2010Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6\u2009\u00b1\u20091.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6\u2009\u00b1\u20090.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7\u2009\u00b1\u20090.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The olfactory cleft of anosmic COVID\u201019 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      4\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 130:2526\u20132531, 2020\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.28993","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T08:58:31Z","timestamp":1594976311000},"page":"2526-2531","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Clinical and Radiological Evaluations of\n                    <scp>COVID<\/scp>\n                    \u201019 Patients With Anosmia: Preliminary Report"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-0845","authenticated-orcid":false,"given":"Jerome R.","family":"Lechien","sequence":"first","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Human Anatomy and Experimental Oncology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology University of Mons (UMons)  Mons Belgium"},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint\u2010Pierre, School of Medicine Universit\u00e9 Libre de Bruxelles  Brussels Belgium"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Michel","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Oto\u2010Rhino\u2010Laryngology\u2013Head and Neck Surgery Aix Marseille University, APHM, IUSTI, La Conception University Hospital  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Radulesco","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Oto\u2010Rhino\u2010Laryngology\u2013Head and Neck Surgery Aix Marseille University, APHM, IUSTI, La Conception University Hospital  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9454-9464","authenticated-orcid":false,"given":"Carlos M.","family":"Chiesa\u2010Estomba","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Hospital Universitario Donostia  San Sebastian Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7789-145X","authenticated-orcid":false,"given":"Luigi A.","family":"Vaira","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Unit University Hospital of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"De Riu","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Unit University Hospital of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh","family":"Sowerby","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Western Ontario  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology King's College  London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Saussez","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force of the Young\u2010Otolaryngologists of the International Federations of Oto\u2010rhino\u2010laryngological Societies (YO\u2010IFOS)  Marseille France"},{"name":"Department of Human Anatomy and Experimental Oncology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology University of Mons (UMons)  Mons Belgium"},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint\u2010Pierre, School of Medicine Universit\u00e9 Libre de Bruxelles  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-05965-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.116"},{"key":"e_1_2_6_4_1","article-title":"Clinical and epidemiological characteristics of 1,420 European patients with mild\u2010to\u2010moderate coronavirus disease 2019 [published online April 30, 2020]","author":"Lechien JR","journal-title":"J Intern Med"},{"key":"e_1_2_6_5_1","article-title":"Sudden and complete 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RadkeJ DittmayerC et al. Olfactory transmucosal SARS\u2010Cov\u20102 invasion as port of central nervous system entry in COVID\u201019 patients. bioRxiv preprint. Available at:https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.04.135012v1. 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