{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:35:06Z","timestamp":1778772906069,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T00:00:00Z","timestamp":1597708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine predictors of increased drain output following type I thyroplasty for glottic insufficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review was conducted for patients who underwent type I thyroplasty for glottic insufficiency from 2014\u20132019. The primary outcome was 24\u2010hour drain output. Increased drain output was defined as &gt;50th percentile for the sample. Univariate logistic regression models and linear regression models were used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 84 patients with a mean age of 58.9 (SD 16.9) years. Twenty\u2010four\u2013hour drain output ranged from 0 to 29\u2009mL with a mean of 9.47 (SD 6.49) mL. Patients with a history of tobacco use (OR 3.33; 95% CI, 1.24\u20138.95; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.017) and prior neck surgery (OR 3.52; 95% CI, 1.26 to 9.83; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.016) were significantly more likely to have increased drain output following surgery; these patients had a mean increase in 24\u2010hour drain output of 3.51\u2009mL (95% CI, 0.52 to 6.51; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.022) and 1.74\u2009mL (95% CI, \u20131.41 to 4.89; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.274), respectively. Type of implant (Gore\u2010Tex vs. Silastic; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.425) and operative technique (unilateral vs. bilateral; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.506) were not significantly associated with drain output.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>History of tobacco use and prior surgery of the neck predict increased drain output following type I thyroplasty surgery. These patients may derive the most benefit from surgical drain placement. More research is needed to confirm these findings and elucidate potential mechanisms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 131:1557\u20131560, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29015","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T05:12:11Z","timestamp":1598591531000},"page":"1557-1560","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of Increased Surgical Drain Output following Type I Thyroplasty for Glottic Insufficiency"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2126-6663","authenticated-orcid":false,"given":"Nicholas R.","family":"Lenze","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of School of Medicine  Chapel Hill North Carolina U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ameer","family":"Ghodke","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of School of Medicine  Chapel Hill North Carolina U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupali N.","family":"Shah","sequence":"additional","affiliation":[{"name":"University of North Carolina Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Buckmire","sequence":"additional","affiliation":[{"name":"University of North Carolina Chapel Hill  Chapel Hill North Carolina 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