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Pooled estimates for patient demographics, presenting findings, complications, and outcomes are determined using random\u2010effects meta\u2010analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010six relevant studies encompassing 1,179 patients met inclusion criteria. Meta\u2010analysis pooled rates of complications: 1.7% (confidence interval [CI] 0.8\u20132.5; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 1.85%) airway complications, 2.8% (CI 1.6\u20133.9; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 13.34%) bilateral recurrent laryngeal nerve paralysis, 2.2% (CI 1.2\u20133.1; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 6.72%) anastomotic dehiscence. Circumferential resection pooled estimates major complications, locoregional recurrence, distal recurrence, overall survival: 14.1% (CI 8.3\u201319.9; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 35.26%), 15% (CI 9.6\u201320.3; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 38.2%), 19.7% (CI 13.7\u201325.8; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 28.83%), 74.5% (CI 64.4\u201384.6; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 85.07%). Window resection estimates: 19.8% (CI 6.9\u201332.8; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 18.83%) major complications, 25.6% (CI 5.1\u201346.1; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.014; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 84.68%) locoregional recurrence, 15.6% (CI 9.7\u201321.5; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 0%) distal recurrence, 77.1% (CI 58\u201396.2; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 78.77%) overall survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Management of invasive thyroid carcinoma may require tracheal resection to achieve locoregional control. Nevertheless, postoperative complications are not insignificant, and therefore this risk cannot be overlooked when counseling patients perioperatively. <jats:italic>Laryngoscope<\/jats:italic>, 131:932\u2013946, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29112","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T15:10:36Z","timestamp":1601305836000},"page":"932-946","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Tracheal Resection in the Management of Thyroid Cancer: An <scp>Evidence\u2010Based<\/scp> Approach"],"prefix":"10.1002","volume":"131","author":[{"given":"Meredith","family":"Allen","sequence":"first","affiliation":[{"name":"Oakland University William Beaumont School of Medicine  Rochester Michigan 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