{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:43:23Z","timestamp":1779165803147,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>There is debate among otolaryngologists and other practitioners about whether upper lip tie contributes to difficulty with breastfeeding and whether upper lip tie and ankyloglossia are linked. Our objectives were to evaluate the anatomy of the upper lip (maxillary) frenulum, to determine if the visual anatomy of the upper lip has an effect on breastfeeding, and to determine whether the occurrence of lip tie and tongue tie are correlated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study of 100 healthy newborns was examined between day of life 3\u20137. Surveys were completed by the mother at the time of the initial exam and 2\u2009weeks later. The maxillary frenulum was graded based on the Stanford and Kotlow classifications by two independent reviewers. Inter\u2010rater reliability and relationships between tongue tie, lip tie, and the infant breastfeeding assessment tool (IBFAT) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Inter\u2010rater reliability showed fair agreement (\u03ba = 0.302) using the Kotlow scale and better agreement using the Stanford classification (\u03ba = 0.458). There was no correlation between the upper lip tie classification and breastfeeding success score. Lastly, there was a modest inverse correlation in the degree of tethering for the tongue and lip.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no correlation between maxillary frenulum grade and comfort with breastfeeding, pain scores, or latch. There was also no relationship between tip to frenulum length (tongue tie) and visualized lip anatomy, suggesting that tongue tie and lip tie may not cluster together in infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2 <jats:italic>Laryngoscope<\/jats:italic>, 131:E1701\u2013E1706, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29140","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T12:15:26Z","timestamp":1601640926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Upper Lip Tie: Anatomy, Effect on Breastfeeding, and Correlation With Ankyloglossia"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5109-8931","authenticated-orcid":false,"given":"Shalini","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Rochester  Rochester New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Rochester  Rochester New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Walker","sequence":"additional","affiliation":[{"name":"Advanced ENT  Voorhees New Jersey U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casey","family":"Rosen\u2010Carole","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Obstetrics and Gynecology University of Rochester  Rochester New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margo K.","family":"McKenna Benoit","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Rochester  Rochester New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817690135"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2017.0116"},{"key":"e_1_2_7_4_1","first-page":"2019","article-title":"Association of feeding evaluation with Frenotomy Rates in infants with breastfeeding difficulties [published online ahead of print, 2019 July 11]","author":"Caloway C","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2019.06.008"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.07.033"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.06.037"},{"key":"e_1_2_7_8_1","first-page":"1","article-title":"The superior labial frenulum in newborns: what is normal?","volume":"4","author":"Santa Maria C","year":"2017","journal-title":"Glob Pediatr Health"},{"key":"e_1_2_7_9_1","unstructured":"KeanN. The Dramatic Rise in Tongue Tie and Lip Tie Treatment.ENTtoday. Available at:https:\/\/www.enttoday.org\/article\/explaining-the-dramatic-rise-in-tongue-tie-and-lip-tie-treatment\/. Published September 6 2019. 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