{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T11:16:14Z","timestamp":1772450174391,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To evaluate the long\u2010term swallowing outcomes after surgical treatment for chronic aspiration in patients treated with radiotherapy for head and neck cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>This was a retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data of patients who underwent radiotherapy for head and neck cancer and who subsequently required a laryngectomy or a tubed supraglottic laryngeal closure (TSLC) for recurrent aspiration pneumonia between 2004 and 2017 were retrieved from a tertiary referral hospital dysphagia clinic. The Functional Oral Intake Scale (FOIS) and the Swallowing Performance and Status Scale (SPSS) were used to assess swallowing function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 17 patients who required surgery for chronic aspiration secondary to radiotherapy for head and neck cancer, two underwent a laryngectomy and 15 a TSLC. During a mean follow\u2010up of 77\u2009months, the FOIS and SPSS scores significantly improved at 12, 24, and 36\u2009months after laryngectomy and TSLC relative to the baseline (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). Both patients who underwent laryngectomy and 11 of the 15 (73.3%) who underwent a TSLC resumed oral feeding. Both laryngectomy patients had episodes of recurrent aspiration pneumonia after surgery due to leakage through the tracheoesophageal puncture or prosthesis, whereas none of the TSLC patients had these episodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A tubed supraglottic laryngeal closure, which is a reversible procedure that preserves the larynx and allows for natural phonation, should be considered an alternative to laryngectomy for the control of chronic aspiration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 131:E1234\u2013E1243, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29217","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T14:49:24Z","timestamp":1604069364000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tubed Supraglottic Laryngeal Closure to Treat Chronic Aspiration After Radiotherapy for Head and Neck Cancer"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2669-9126","authenticated-orcid":false,"given":"Peter K. M.","family":"Ku","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery United Christian Hospital, Kwun Tong and Tseung Kwan O Hospital  Tseung Kwan O Hong Kong"},{"name":"Department of Otorhinolaryngology, Head and Neck Surgery The Chinese University of Hong Kong, Prince of Wales Hospital  Shatin Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander C.","family":"Vlantis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery The Chinese University of Hong Kong, Prince of Wales Hospital  Shatin Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9162-282X","authenticated-orcid":false,"given":"Ryan H. W.","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery United Christian Hospital, Kwun Tong and Tseung Kwan O Hospital  Tseung Kwan O Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenon W. C.","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery United Christian Hospital, Kwun Tong and Tseung Kwan O Hospital  Tseung Kwan O Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osan Y. M.","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery United Christian Hospital, Kwun Tong and Tseung Kwan O Hospital  Tseung Kwan O Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas S. 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