{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:30:47Z","timestamp":1747150247935,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T00:00:00Z","timestamp":1606435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Despite improvements in the treatment of juvenile angiofibroma (JA), the rate of persistence (pJA) is still not negligible. In the present study, we assessed the value of early postoperative magnetic resonance imaging (MRI) in depicting unintentional pJAs and designed a MRI\u2010driven decisional flow\u2010chart for pJA management and follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing early postoperative MRI after endoscopic resection of JA in the Unit of Otorhinolaryngology \u2013 ASST Spedali Civili, University of Brescia from 2007 to 2017 were enrolled. MRI was defined as negative or positive based on defined radiological criteria. The diagnostic performance of MRI was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis included 26 patients, with a mean age of 16.5\u2009years (range, 11\u201325). Early MRI was negative for pJA in 21 (80.8%) patients and positive in five (19.2%). No patient with a negative finding was found positive at subsequent follow\u2010up MRIs. The accuracy of a positive finding was confirmed by pathologic examination (three cases) or follow\u2010up MRIs (two cases). The diagnostic performance of MRI was excellent with sensitivity and specificity of 100%. An MRI\u2010driven flow\u2010chart for pJA management and follow\u2010up was designed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early postoperative MRI demonstrated a high diagnostic accuracy in the detection of unintentional pJA. Our MRI\u2010driven strategy and decisional flow\u2010chart could aid in the decision\u2010making process in the management of pJA and definition of postoperative surveillance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 131:E2436\u2013E2441, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29293","type":"journal-article","created":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T18:00:48Z","timestamp":1606500048000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Early Postoperative Magnetic Resonance in the Diagnosis of Persistent Juvenile Angiofibroma"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1580-3928","authenticated-orcid":false,"given":"Alberto","family":"Schreiber","sequence":"first","affiliation":[{"name":"Unit of Otorhinolaryngology\u2010Head and Neck Surgery, ASST Spedali 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