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The main inclusion criteria for eligible articles for meta\u2010analysis were patients with benign or malignant thyroid pathologies who underwent total thyroidectomy, utilization of optical techniques to support PGs preservation, the availability of calcium and\/or PTH levels. The primary outcome was to evaluate the variation of calcium and PTH levels when adopting optical technologies compared to standard naked\u2010eye surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 13 papers with 1484 procedures were included. Pooled proportion for short\u2010 and medium\u2010term hypocalcemia rates were 8% (95% CI, 5%:11%) and 1% (95% CI, 0%:4%) for optical techniques, while for naked\u2010eye surgery were 15% (95% CI, 9%:23%) and 5% (95% CI, 2%:9%), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Optical technologies reduced short and medium term hypocalcemia compared to conventional surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA <jats:italic>Laryngoscope<\/jats:italic>, 131:1683\u20131692, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29297","type":"journal-article","created":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T13:05:31Z","timestamp":1606568731000},"page":"1683-1692","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Autofluorescence and Indocyanine Green in Thyroid Surgery: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"131","author":[{"given":"Diego","family":"Barbieri","sequence":"first","affiliation":[{"name":"Division of Head and Neck department, Otorhinolaryngology unit IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7447-0994","authenticated-orcid":false,"given":"Pietro","family":"Indelicato","sequence":"additional","affiliation":[{"name":"Division of Head and Neck department, Otorhinolaryngology unit IRCCS San Raffaele Scientific Institute  Milan Italy"},{"name":"School of Medicine Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Vinciguerra","sequence":"additional","affiliation":[{"name":"Division of Head and Neck department, Otorhinolaryngology unit IRCCS San Raffaele Scientific Institute  Milan Italy"},{"name":"School of Medicine Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Di Marco","sequence":"additional","affiliation":[{"name":"Urological Research Institute (URI), Division of experimental oncology IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Formenti","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Vita\u2010Salute San Raffaele University and IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6472-3484","authenticated-orcid":false,"given":"Matteo","family":"Trimarchi","sequence":"additional","affiliation":[{"name":"Division of Head and Neck department, Otorhinolaryngology unit IRCCS San Raffaele Scientific Institute  Milan Italy"},{"name":"School of Medicine Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Bussi","sequence":"additional","affiliation":[{"name":"Division of Head and Neck department, Otorhinolaryngology unit IRCCS San Raffaele Scientific Institute  Milan Italy"},{"name":"School of Medicine Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-003-6903-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9384"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2017.09.14"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.3.304"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900459"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2013.06.046"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2020.01.04"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-4-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2019.4613"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_6_12_1","volume-title":"A Language and Environment for Statistical Computing","author":"R Core Team R","year":"2019"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.01686"},{"key":"e_1_2_6_14_1","first-page":"40","article-title":"Meta: an R package for meta\u2010analysis","volume":"7","author":"Schwarzer G","year":"2007","journal-title":"R News"},{"key":"e_1_2_6_15_1","volume-title":"RStudio: Integrated Development Environment for R","author":"RStudio Team","year":"2019"},{"key":"e_1_2_6_16_1","unstructured":"WellsGA SheaBJ O'ConnellD et al.Newcastle\u2010Ottawa Quality Assessment Scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analyses; 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