{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:18:54Z","timestamp":1792840734802,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:00:00Z","timestamp":1609113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To evaluate the outcomes of endonasal repair of septal perforations utilizing opposing bilateral rotational flaps and a periosteum interposition graft.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of a single surgeon, tertiary referral center experience of patients who underwent septal perforation repair. Patient demographics, etiology of perforation, closure rate, and complication data were obtained. Patients screening positively for cocaine use or anti\u2010neutrophil cytoplasmic antibodies (ANCA) were not offered repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 104 patients were included, 65 male and 39 female with mean age of 45.4\u2009years. Etiology of perforations included prior surgery in 45, trauma in 15, and unknown in 44, and the average perforation size in each etiologic group were 1.35\u2009cm, 1.25\u2009cm, and 1.30\u2009cm, respectively. The greatest dimension of perforations repaired ranged from 0.5\u2009cm to 1.5\u2009cm. The overall success rate was 87.5% at 6\u2009month follow\u2010up. Successful closure was achieved in 95.6%, 86.7%, and 79.5%, respectively (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u20095.264, <jats:italic>P<\/jats:italic>\u00a0=\u2009.0218).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our described technique is a reliable endonasal approach with predictable outcomes in septal perforations up to 1.5\u2009cm in size. Having an unknown etiology of septal perforation may be a risk factor for failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 131:1497\u20131500, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29347","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T20:41:38Z","timestamp":1609188098000},"page":"1497-1500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Septal Perforation Repair Using Bilateral Rotational Flaps With Interposed Mastoid Periosteal Graft"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3155-1828","authenticated-orcid":false,"given":"Weitao","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Rochester  Rochester New York U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0793-1532","authenticated-orcid":false,"given":"Aurora","family":"Vincent","sequence":"additional","affiliation":[{"name":"Otolaryngology and Facial Plastic Surgery Associates  Fort Worth Texas U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1123-4385","authenticated-orcid":false,"given":"Tom","family":"Shokri","sequence":"additional","affiliation":[{"name":"Otolaryngology and Facial Plastic Surgery Associates  Fort Worth Texas U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hilger","sequence":"additional","affiliation":[{"name":"Hilger Facial Plastic Clinic  Minneapolis Minnesota U.S.A."},{"name":"Division of Facial Plastic Surgery in the Department of Otolaryngology University of Minnesota  Minneapolis Minnesota U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadranko","family":"Ducic","sequence":"additional","affiliation":[{"name":"Otolaryngology and Facial Plastic Surgery Associates  Fort Worth Texas U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510700566X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200308000-00031"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1988.tb00281.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.1.2.97"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1988.01860190043019"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100145025"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800090064010"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860280033012"},{"key":"e_1_2_6_10_1","first-page":"165","article-title":"Closure of nasal septal perforations","volume":"23","author":"Mina MMF","year":"1994","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100142744"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198012000-00007"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199302000-00004"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890030057009"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1986.03780020048011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.1.73"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199901000-00012"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2003.00654.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1258\/002221503321046649"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1977.87.11.1942"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011906939"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100121206"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100137569"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198809000-00017"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32834dfb21"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2010.05.006"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29347","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.29347","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T19:38:50Z","timestamp":1693424330000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.29347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,28]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/lary.29347"],"URL":"https:\/\/doi.org\/10.1002\/lary.29347","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,28]]},"assertion":[{"value":"2020-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}