{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T22:47:01Z","timestamp":1768258021389,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of absorbable steroid\u2010impregnated nasal packing on postoperative outcomes following functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review of the literature was conducted as per Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) guidelines. Twelve databases (including Journals@Ovid, Embase\u00ae, Medline\u00ae, EBM Reviews and Joanna Briggs Institute EBP Database) were searched using relevant keywords and expanded with corresponding MeSH\/Emtree terms. Results were narrowed to English articles assessing the efficacy of absorbable packing impregnated with steroids post\u2010production placed at time of surgery under general anesthetic, with hollow\u2010lumen devices and devices inserted in\u2010office excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight studies met criteria and were included in this review. Five evaluated the efficacy of the intervention in only CRS with nasal polyposis (CRSwNP) patients, two included all subtypes of CRS, and one included only CRS without nasal polyposis (CRSsNP). Of the eight studies, four studied the efficacy of Nasopore\u00ae, three studied bioabsorbable gels, and one studied bioabsorbable calcium alginate. Four studies applied triamcinolone as the operative steroid, with the other studies utilizing betamethasone, budesonide, mometasone, and dexamethasone. Seven studies demonstrated statistically significant improvements in endoscopic outcomes using validated scoring scales, albeit at differing timepoints. The one study which included only CRSsNP patients failed to find a significant difference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Steroid\u2010impregnated nasal packing appears to have positive effects on postoperative endoscopic outcomes in CRSwNP patients undergoing FESS. Additional research is needed to evaluate the efficacy of these interventions in more recently defined subtypes of CRS, and whether these interventions differ in their efficacy in eosinophilic and non\u2010eosinophilic CRS. <jats:italic>Laryngoscope<\/jats:italic>, 131:1704\u20131714, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29350","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T13:06:26Z","timestamp":1609765586000},"page":"1704-1714","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Efficacy of Absorbable Steroid\u2010Impregnated Nasal Packing in <scp>Functional Endoscopic Sinus Surgery<\/scp> for Chronic Rhinosinusitis: A Systematic Review"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7946-8874","authenticated-orcid":false,"given":"Michael","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery Gosford Hospital, NSW Health\u2014Central Coast Local Health District  Gosford New South Wales Australia"},{"name":"School of Medicine and Public Health\u2014Faculty of Health and Medicine The University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery Gosford Hospital, NSW Health\u2014Central Coast Local Health District  Gosford New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Singh","family":"Shashinder","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery Gosford Hospital, NSW Health\u2014Central Coast Local Health District  Gosford New South Wales Australia"},{"name":"School of Medicine and Public Health\u2014Faculty of Health and Medicine The University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.401"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21695_c"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2009.23.3355"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2016.30.4297"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-019-0350-y"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199301000-00001"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:30:3:217"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900601"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199901000-00006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26391"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26741"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3950"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.20072"},{"key":"e_1_2_7_15_1","first-page":"349","article-title":"Preferred reporting items for systematic review and meta\u2010analysis protocols (PRISMA\u2010P) 2015: elaboration and explanation","volume":"7647","author":"Shamseer L","year":"2015","journal-title":"BMJ"},{"key":"e_1_2_7_16_1","unstructured":"Centre for Reviews and Dissemination UoY.PROSPERO\u2014International Prospective Register of Systematic Reviews. 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