{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T21:10:13Z","timestamp":1770066613097,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>This study aimed to evaluate the olfactory status in children with laboratory confirmed SARS\u2010CoV\u20102 using subjective and psychophysical methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective clinical cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a prospective clinical cross\u2010sectional study of 79 children with COVID\u201019. The 21st item of SNOT\u201022 questionnaire and odor identification test were used for smell assessment. Children were examined twice during the hospitalization, and a telephone survey was conducted 60\u2009days after hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Immediately after confirmation of COVID\u201019, smell impairment was detected in 86.1% of children by means of the Identification test and in 68.4% of children by means of the survey (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.010). After 5\u2009days survey revealed a statistically significant decrease in the number of patients with hyposmia (41 out of 79, 51.9%). On the first visit, the mean Identification test score corresponded to \u201chyposmia\u201d (9.5\u2009\u00b1\u20092.7), while on the second visit, the average value was 13.1\u2009\u00b1\u20091.9, which corresponded to \u201cnormosmia.\u201d According to the telephone survey, recovery of the olfactory function occurred within 10\u2009days in 37 of 52 patients (71.2%), 11 to 29\u2009days \u2010 in 12 children (23.1%), and later than 30\u2009days \u2010 in three cases (5.7%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the pediatric population, olfactory dysfunction is an early and common symptom of COVID\u201019. There is a trend to quick recovery of olfactory function in children with COVID\u201019. The overwhelming majority of patients (94.3%) had no subjective olfactory complaints by the end of the first month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 131:E2475\u2013E2480, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29403","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T19:06:59Z","timestamp":1610737619000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Smell Status in Children Infected with <scp>SARS\u2010CoV<\/scp>\u20102"],"prefix":"10.1002","volume":"131","author":[{"given":"Yury","family":"Rusetsky","sequence":"first","affiliation":[{"name":"Otorhinolaryngological surgical department with a group of head and neck diseases National Medical Research Center of Children's Health  Moscow Russia"},{"name":"Department of ear, nose and throat diseases Central State Medical Academy  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Meytel","sequence":"additional","affiliation":[{"name":"Otorhinolaryngological surgical department with a group of head and neck diseases National Medical Research Center of Children's Health  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6537-0510","authenticated-orcid":false,"given":"Zhanna","family":"Mokoyan","sequence":"additional","affiliation":[{"name":"Department of ear, nose and throat diseases I.M.Sechenov First Moscow State Medical University (Sechenov University)  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrey","family":"Fisenko","sequence":"additional","affiliation":[{"name":"Otorhinolaryngological surgical department with a group of head and neck diseases National Medical Research Center of Children's Health  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Babayan","sequence":"additional","affiliation":[{"name":"Otorhinolaryngological surgical department with a group of head and neck diseases National Medical Research Center of Children's Health  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulyana","family":"Malyavina","sequence":"additional","affiliation":[{"name":"Otorhinolaryngological surgical department with a group of head and neck diseases National Medical Research Center of Children's Health  Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.114"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820922992"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-05965-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-05968-y"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06069-6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30154-9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-0702"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2020.04.007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","unstructured":"QiuC CuiC HautefortC et al.Olfactory and gustatory dysfunction as an early identifier of COVID\u201019 in adults and children: an international multicenter study.2020;163:714\u2013721.https:\/\/doi.org\/10.1101\/2020.05.13.20100198.","DOI":"10.1177\/0194599820934376"},{"key":"e_1_2_6_11_1","unstructured":"Ages & Stages. Available at:HealthyChildren.org.https:\/\/www.healthychildren.org\/english\/ages-stages\/pages\/default.aspx. Published 2020. Accessed September 14 2020."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2020.1155"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13505"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0173-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000006601"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.29403","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T22:26:08Z","timestamp":1693347968000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.29403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,18]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/lary.29403"],"URL":"https:\/\/doi.org\/10.1002\/lary.29403","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,18]]},"assertion":[{"value":"2020-09-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}