{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T15:51:53Z","timestamp":1773244313834,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T00:00:00Z","timestamp":1617840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102021\u2010R1C100498611 and NRF\u20102018\u2010R1D1A1A02085328"],"award-info":[{"award-number":["NRF\u20102021\u2010R1C100498611 and NRF\u20102018\u2010R1D1A1A02085328"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>This study investigated the impacts of air pollution and meteorological factors on the occurrence of epiglottitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A nested case\u2010control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants \u226540\u2009years old in the Korean National Health Insurance Service\u2010Health Screening Cohort were analyzed. A total of 2,615 epiglottitis patients and 10,460 matched control participants were analyzed. The odds ratios (ORs) for epiglottitis associated with meteorological and air pollution factors, including sulfur dioxide (SO<jats:sub>2<\/jats:sub>, ppb), nitrogen dioxide (NO<jats:sub>2<\/jats:sub>, ppb), ozone (O<jats:sub>3<\/jats:sub>, ppb), and carbon monoxide (CO, ppm), after 3, 7, 15, and 30\u2009days of exposure were analyzed using conditional logistic regression adjusted for total cholesterol, blood pressure, fasting blood glucose, obesity, smoking, alcohol consumption, prior upper respiratory infection, tonsillectomy, immunocompromise, autoimmune disease, and the Charlson comorbidity index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The daily temperature range and NO<jats:sub>2<\/jats:sub> exposure after 3\u2009days were associated with increased rates of epiglottitis (OR\u00a0=\u00a01.03, 95% confidence interval [CI]\u00a0=\u00a01.02\u20131.05 for temperature range and OR\u00a0=\u00a01.78, 95% CI\u00a0=\u00a01.14\u20132.77 for NO<jats:sub>2<\/jats:sub>, respectively). These results were generally consistent at 7, 15, and 30\u2009days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The temperature range and NO<jats:sub>2<\/jats:sub> exposure for 3, 7, 15, and 30\u2009days were positively related to the occurrence of adult epiglottitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 131:2483\u20132489, 2021<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29560","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T12:55:09Z","timestamp":1617886509000},"page":"2483-2489","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Short\u2010Term Exposure to Air Pollution and Epiglottitis: A Nested Case\u2013Control Study"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7361-4930","authenticated-orcid":false,"given":"So Young","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head &amp; Neck Surgery, CHA Bundang Medical Center CHA University  Seongnam South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanyang","family":"Min","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory Hallym University College of Medicine  Anyang South Korea"},{"name":"Graduate School of Public Health Seoul National University  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Myoung","family":"Yoo","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory Hallym University College of Medicine  Anyang South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bumjung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head &amp; Neck Surgery Hallym University College of Medicine  Anyang South 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