{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:14:26Z","timestamp":1787062466607,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T00:00:00Z","timestamp":1624406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>To evaluate survival for nasopharyngeal carcinoma in relation to socioeconomic status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) Census Tract\u2010level Socioeconomic Status Database (2000\u20132016).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with nasopharyngeal carcinoma diagnosed between 2000 and 2016 were identified. Data were stratified based on socioeconomic status, divided into three groups: group 1 being the poorest and group 3 the wealthiest. Univariate analysis as well as multivariate Cox regression analysis adjusted for individual variables was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 5,527 patients were included in the study, with 33% in group 1, 34% in group 2, and 33% in group 3. There was a significant difference between groups in regard to age at diagnosis, race, histologic subtype, overall stage, tumor stage, nodal stage, and whether or not they received radiation. Patients in group 1, the poorest socioeconomic status, were more likely to be young (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.003), black (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001), present with higher overall stage (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.009), tumor stage (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.01), and nodal stage (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02), and less likely to receive radiation (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.005). In multivariate analysis, there was a significant difference in survival between the groups, with group 1 patients less likely to survive compared to group 3 (hazard ratio\u00a0=\u00a01.28; 95% CI 1.07\u20131.57).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients in the poorest socioeconomic status presented with more advanced nasopharyngeal cancer and were less likely to receive radiation when compared with individuals of higher socioeconomic status. The poorest socioeconomic status groups were less likely to survive from their disease when controlling for other variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      NA\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 131:2719\u20132723, 2021\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.29702","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T07:11:49Z","timestamp":1624432309000},"page":"2719-2723","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Socioeconomic Status and Survival in Nasopharyngeal Carcinoma: A\n                    <scp>Population\u2010Based<\/scp>\n                    Study"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6115-7031","authenticated-orcid":false,"given":"Sabrina","family":"Brody\u2010Camp","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Ochsner Health System  New Orleans Louisiana U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward D.","family":"McCoul","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Ochsner Health System  New Orleans Louisiana U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Tulane University School of Medicine  New Orleans Louisiana U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Lefante","sequence":"additional","affiliation":[{"name":"Department of Global Biostatistics and Data Science Tulane University School of Public Health and Tropical Medicine  New Orleans Louisiana U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rizwan","family":"Aslam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Tulane University School of Medicine  New Orleans Louisiana U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,23]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Cancer.net.Nasopharyngeal Cancer: Statistics. American Society of Clinical Oncology 2020. Available at:https:\/\/www.cancer.net\/cancer-types\/nasopharyngeal-cancer\/statistics"},{"key":"e_1_2_6_3_1","volume-title":"Cancer Facts & Figures: 2017","year":"2020"},{"key":"e_1_2_6_4_1","unstructured":"Cancer.org.Treatment Options by Stage of Nasopharyngeal Cancer. American Cancer Society 2020. Available at:https:\/\/www.cancer.org\/cancer\/nasopharyngeal-cancer\/treating\/by-stage.html"},{"key":"e_1_2_6_5_1","first-page":"597","article-title":"Socioeconomic factors in head and neck cancer","volume":"37","author":"Johnson S","year":"2008","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25521"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0149886"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-013-0310-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011240019516"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology9040084"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12371"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.102288"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2013.08.008"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28099"},{"key":"e_1_2_6_15_1","unstructured":"Healthy People 2020. Social determinants of health. Available at:https:\/\/www.healthypeople.gov\/2020\/topics-objectives\/topic\/social-determinants-of-health#two. Accessed October 2020."},{"key":"e_1_2_6_16_1","unstructured":"World Health Organization Commission on Social Determinants of Health.Closing the Gap in a Generation: Health equity through action on the social determinants of health. Available at:http:\/\/www.who.int\/social_determinants\/en. Accessed October 2020."},{"key":"e_1_2_6_17_1","volume-title":"Closing the Gap in a Generation: Health Equity through Action on the Social Determinants of Health: Commission on Social Determinants of Health Final Report","author":"WHO Commission on Social Determinants of Health","year":"2008"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.currproblcancer.2012.03.011"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29702","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.29702","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T12:11:49Z","timestamp":1693224709000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.29702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,23]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1002\/lary.29702"],"URL":"https:\/\/doi.org\/10.1002\/lary.29702","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,23]]},"assertion":[{"value":"2021-03-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}