{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:35:43Z","timestamp":1790174143900,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T00:00:00Z","timestamp":1626912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>Laryngeal chondrosarcomas are rare malignancies with a spectrum of presentations due to varying size, local extension, and biological behavior. Moreover, these neoplasms have differing effects on respiration, phonation, and deglutition. Consequently, it is valuable to assess endoscopic and transcervical treatment strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was done from 2001 to 2020; 25 patients were identified with laryngeal chondrosarcomas. Their tumor pathology and treatment were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All 25 chondrosarcomas were in the posterior cricoid and arose in proximity to at least one cricoarytenoid joint: 23 of 25 grade I\u2013II (low\u2010mid), one of 25 grade II\u2013III (mid\u2010high), and one of 25 grade III (high). Some tumor was left in 23 of 25 to preserve cricoarytenoid\u2010joint function. There were no known disease\u2010specific deaths (~8\u2010year median follow\u2010up). Final surgical treatment in 24 of 25 was: 13 of 25 transcervical partial laryngectomy, 7 of 25 transoral\u2010endoscopic removal, 4 of 25 total laryngectomy, and 1 of 25 observation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this series, unresected intercurrent disease with laryngeal chondrosarcomas was not life\u2010threatening. Therefore, disease was typically left in the posterior cricoid region to preserve mobility of at least one cricoarytenoid joint. This philosophy employed an ultra\u2010function\u2010sparing conservation approach that preserved and\/or restored optimal voice, airway patency and swallowing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      4\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 132:169\u2013176, 2022\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.29762","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T04:45:37Z","timestamp":1626929137000},"page":"169-176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Surgical Treatment Strategies for Laryngeal Chondrosarcomas: A Single Institution Investigation"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6311-8389","authenticated-orcid":false,"given":"Steven M.","family":"Zeitels","sequence":"first","affiliation":[{"name":"Department of Surgery\u2014Harvard Medical School, Division of Laryngeal Surgery Massachusetts General Hospital  Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon J.","family":"Baird","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Chicago, Section of Otolaryngology\u2014Head and Neck Surgery  Chicago Illinois U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941112000908"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200207000-00002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/095952871600700109"},{"key":"e_1_2_6_5_1","volume-title":"Malignant Disease (Sarcoma and Carcinoma) of the Larynx","author":"Butlin HT","year":"1883"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197005000-00007"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949710600202"},{"key":"e_1_2_6_8_1","first-page":"411","article-title":"Suspension laryngoscopy in the treatment of malignant disease of the hypopharynx and larynx","volume":"16","author":"New GB","year":"1941","journal-title":"Mayo Clin 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