{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T11:57:24Z","timestamp":1781870244852,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Mandibular distraction osteogenesis (MDO) is a safe and effective surgery to address respiratory and feeding issues due to micrognathia in patients with Robin Sequence (RS). Previous studies examining postoperative complications in neonates receiving MDO have considered 4\u2009kg as the cut\u2010off for low weight; however, an increasing number of MDO interventions are performed in infants &lt;4\u2009kg. To determine if a weight &lt;3\u2009kg at time of MDO is a risk factor for postoperative complications or need for subsequent tracheostomy or gastrostomy tube (G\u2010tube).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of all infants &lt;6\u2009months of age undergoing MDO at two tertiary pediatric hospitals from 2008 to 2018. Demographic data, syndromic status, weight, and age at time of surgery, length of postoperative hospital stay, and postoperative outcomes were recorded including tracheostomy placement, G\u2010tube placement, hardware infection, reintubation, facial\/marginal mandibular nerve damage, and need for revision MDO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010nine patients with RS were included. The mean age at MDO was 25\u2009\u00b1\u200920\u2009days and mean weight was 3.32\u2009\u00b1\u20090.44\u2009kg. There was no statistically significant correlation between weight (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.699) or age (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.422) and unfavorable postoperative outcomes. No patients (0%) underwent tracheostomy pre\u2010MDO. Two patients (2.9%) required tracheostomy postsurgery; neither was &lt;3\u2009kg. Eight patients (11.6%) required a G\u2010tube postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Newborns &lt;3\u2009kg who undergo MDO experience the same rates of success and complication as larger infants, suggesting that MDO is a safe and efficacious procedure in infants less than 3\u2009kg. <jats:italic>Laryngoscope<\/jats:italic>, 132:1295\u20131299, 2022<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29877","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T01:14:44Z","timestamp":1634174084000},"page":"1295-1299","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Safety and Efficacy of Mandibular Distraction Osteogenesis Among Infants Less Than 3\u2009kg"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6867-0666","authenticated-orcid":false,"given":"Zahrah","family":"Taufique","sequence":"first","affiliation":[{"name":"Department of ENT and Facial Plastic Surgery Children's Minnesota  Minneapolis Minnesota U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Minnesota Medical School  Minneapolis Minnesota U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Ebert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Minnesota Medical School  Minneapolis Minnesota U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily C.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Tufts Children's Hospital, Tufts Medical Center  Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan","family":"Zavala","sequence":"additional","affiliation":[{"name":"Department of ENT and Facial Plastic Surgery Children's Minnesota  Minneapolis Minnesota U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0856-3396","authenticated-orcid":false,"given":"Andrew R.","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Tufts Children's Hospital, Tufts Medical Center  Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7244-3247","authenticated-orcid":false,"given":"Brianne B.","family":"Roby","sequence":"additional","affiliation":[{"name":"Department of ENT and Facial Plastic Surgery Children's Minnesota  Minneapolis Minnesota U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Minnesota  Minneapolis 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