{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:44:06Z","timestamp":1792791846343,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:00:00Z","timestamp":1635292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To compare the 12\u2010month evolution of voice quality outcomes in patients who benefited from types 1\u20132 transoral CO<jats:sub>2<\/jats:sub> laser cordectomy (TLC) for an early\u2010stage vocal fold squamous cell carcinoma (VFSCC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective uncontrolled study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty patients with cT1 VFSCC were consecutively recruited from a single medical center. Thirty patients benefited from type 1 TLC, while type 2 TCL was performed in 30 patients. The following voice quality outcomes were evaluated at baseline, 3\u2010, 6\u2010, and 12\u2010month post\u2010TLC: voice handicap index (VHI), GRBAS, speech rate, maximum phonation time (MPT), and acoustic parameters. Voice quality evolution was compared between type 1 and type 2 TLC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010seven patients completed the evaluations. Type 1 TLC patients reported significant improvements of VHI, grade of dysphonia, and breathiness at 3\u2010, 6\u2010, and 12\u2010month post\u2010TLC. Speech rate and jitter values improved 6\u2010 and 12\u2010month post\u2010TLC. A few voice quality outcomes reported 3\u2010 or 6\u2010month post\u2010TLC improvements in type 2 TLC group, while VHI, grade of dysphonia improved at 6\u2010 and 12\u2010month post\u2010TLC. MPT significantly decreased at 6\u2010 and 12\u2010month post\u2010TLC, while there were no acoustic measurement changes in type 2 TLC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The effect of TLC on voice quality may depend on the type of TLC. Type 1 TLC was associated with faster voice quality improvements compared with type 2 TLC. VHI and dysphonia grade were identified as the most relevant tool of voice changes irrespective to the TLC type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 132:1421\u20131426, 2022<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29924","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T11:54:21Z","timestamp":1635335661000},"page":"1421-1426","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Evolution of Voice Quality in Type 1\u20132 Transoral <scp>CO<sub>2<\/sub><\/scp> Laser Cordectomy: A Prospective Comparative Study"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-0845","authenticated-orcid":false,"given":"Jerome R.","family":"Lechien","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Elsan Hospital  Paris France"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery CHU de Bruxelles, CHU Saint\u2010Pierre, School of Medicine  Brussels Belgium"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Foch Hospital, School of Medicine Paris Saclay University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Crevier\u2010Buchman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Foch Hospital, School of Medicine Paris Saclay University  Paris France"},{"name":"Phonetics and Phonology Lab CNRS UMR7018, University of Sorbonne\u2010Nouvelle  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta P.","family":"Circiu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Foch Hospital, School of Medicine Paris Saclay University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4194-6145","authenticated-orcid":false,"given":"Quentin","family":"Lisan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Foch Hospital, School of Medicine Paris Saclay University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Hans","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Foch Hospital, School of Medicine Paris Saclay University  Paris France"},{"name":"Phonetics and Phonology Lab CNRS UMR7018, University of Sorbonne\u2010Nouvelle  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21528"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2003.41731"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28240"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050050228"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0279-z"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941312200308"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25267"},{"key":"e_1_2_7_9_1","first-page":"307","article-title":"The Voice Handicap Index: impact of the translation in French on the validation","volume":"125","author":"Woisard V","year":"2004","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"e_1_2_7_10_1","volume-title":"Clinical Examination of Voice","author":"Hirano M","year":"1981"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20625"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000217557.45491.BD"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06751-3"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320906328"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322592"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2011.20621"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25789"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21914"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2012.01.003"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2019.08.022"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500085"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3181b2b36b"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29924","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.29924","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.29924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T22:27:27Z","timestamp":1692829647000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.29924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,27]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1002\/lary.29924"],"URL":"https:\/\/doi.org\/10.1002\/lary.29924","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,27]]},"assertion":[{"value":"2021-08-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}