{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:09:09Z","timestamp":1790680149915,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T00:00:00Z","timestamp":1637884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:label\/><jats:p>The aim of this study is to investigate the clinical profile of patients who developed coronavirus disease 2019 (COVID\u201019) after full vaccination. Demographic, epidemiological and clinical data were collected through medical records and online patient\u2010reported outcome questionnaire from patients who developed symptomatic SARS\u2010CoV\u20102 infection, confirmed by nasopharyngeal swab, at least 2\u2009weeks after completion of vaccination. A total of 153 subjects were included. The most frequent symptoms were: asthenia (82.4%), chemosensory dysfunction (63.4%), headache (59.5%), runny nose (58.2%), muscle pain (54.9%), loss of appetite (54.3%), and nasal obstruction (51.6%). Particularly, 62.3% and 53.6% of subjects reported olfactory and gustatory dysfunction, respectively. Symptom severity was mild or moderate in almost all cases. Chemosensory dysfunctions have been observed to be a frequent symptom even in subjects who contracted the infection after full vaccination. For this reason, the sudden loss of smell and taste could continue to represent a useful and specific diagnostic marker to raise the suspicion of COVID\u201019 even in vaccinated subjects. In the future, it will be necessary to establish what the recovery rate is in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 132:419\u2013421, 2022<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29964","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T11:33:40Z","timestamp":1637667220000},"page":"419-421","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["New Onset of Smell and Taste Loss Are Common Findings Also in Patients With Symptomatic <scp>COVID<\/scp>\u201019 After Complete Vaccination"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7789-145X","authenticated-orcid":false,"given":"Luigi A.","family":"Vaira","sequence":"first","affiliation":[{"name":"Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences University of Sassari  Sassari Italy"},{"name":"Biomedical Science PhD School, Biomedical Science Department University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"De Vito","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit, Department of Medical, Surgical and Experimental Sciences University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-0845","authenticated-orcid":false,"given":"Jerome R.","family":"Lechien","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force Young\u2010Otolaryngologists of the International Federation of Oto\u2010rhino\u2010laryngological Societies  Paris France"},{"name":"Department of Human and Experimental Oncology, Faculty of Medicine UMONS Research Institute for Health Sciences and Technology University of Mons  Mons Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9454-9464","authenticated-orcid":false,"given":"Carlos M.","family":"Chiesa\u2010Estomba","sequence":"additional","affiliation":[{"name":"COVID\u201019 Task Force Young\u2010Otolaryngologists of the International Federation of Oto\u2010rhino\u2010laryngological Societies  Paris France"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Hospital Universitario Donostia  San Sebastian Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-6597","authenticated-orcid":false,"given":"Miguel","family":"Mayo\u2010Y\u00e0\u00f1ez","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology, Head and Neck Surgery Department University Hospital Complex of A Coru\u00f1a  A Coru\u00f1a 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Sciences University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Babudieri","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit, Department of Medical, Surgical and Experimental Sciences University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Boscolo\u2010Rizzo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Department King's College  London U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"De Riu","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences 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