{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:28:56Z","timestamp":1790706536289,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:00:00Z","timestamp":1639180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL154429"],"award-info":[{"award-number":["R01 HL154429"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL123557"],"award-info":[{"award-number":["R01 HL123557"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To establish the utility of anatomic optical coherence tomography (aOCT) in evaluating internal nasal valve (INV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Anatomic specimen imaging study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fresh\u2010harvested human specimen heads were evaluated using both computed tomography (CT) imaging as well as using aOCT. Scans were performed at three time points: 1) After septoplasty for cartilage harvest, 2) after placement of butterfly graft (BFG), and 3) after placement of bilateral spreader grafts (SG). Imaging data were then converted into 3D models of the nasal airway. CT\u2010 and aOCT\u2010generated models were compared by both static volumetric analysis and computational fluid dynamics (CFD) to predict nasal resistance and pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Scans using aOCT showed comparable results to CT in terms of volumetric parameters both before and after intervention. Analysis of aOCT data by CFD demonstrated decrease in pressure after SG or BFG intervention. No statistically significant difference was observed when comparing CT\u2010 and aOCT\u2010generated calculations of pressure or resistance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The INV can be imaged in a static fashion using aOCT technology. Advantages over traditional CT imaging include lack of exposure to radiation and rapid scan time. In addition, in\u2010office use is possible as aOCT technology develops. Further investigation will be necessary to define the role of aOCT in the dynamic evaluation of this vital component of the nasal airway.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 132:2148\u20132156, 2022<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.29979","type":"journal-article","created":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T11:55:35Z","timestamp":1639223735000},"page":"2148-2156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Anatomic Optical Coherence Tomography (<scp>aOCT<\/scp>) for Evaluation of the Internal Nasal Valve"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5995-0161","authenticated-orcid":false,"given":"Candace M.","family":"Waters","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Wake Forest Baptist Medical Center  Winston\u2010Salem North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesley H.","family":"Stepp","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Conduff","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Balakrishnan","sequence":"additional","affiliation":[{"name":"Department of Physics University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruofei","family":"Bu","sequence":"additional","affiliation":[{"name":"Department of Physics University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L.","family":"Oldenburg","sequence":"additional","affiliation":[{"name":"Department of Physics University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1969-6373","authenticated-orcid":false,"given":"Julia S.","family":"Kimbell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Shockley","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph Madison","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina 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