{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:27:44Z","timestamp":1790310464291,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"S8","license":[{"start":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T00:00:00Z","timestamp":1641772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>To identify the imaging characteristics associated with better hearing outcomes found in cochleovestibular nerve (CVN) abnormalities treated with hearing aids and\/or cochlear implantation (CI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was undertaken of 69 ears with CVN abnormalities seen on magnetic resonance imaging (MRI) treated at a tertiary referral academic center analyzing the clinical features, imaging characteristics, and hearing data. We searched for associations among the hearing and imaging data, hypothesizing that the imaging data was not a good indicator of hearing function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In univariable analysis of all those who underwent aided testing (hearing aid and CI), health status (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u2009.016), internal auditory canal (IAC) midpoint diameter (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u2009.001), and number of nerves in the IAC (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u2009.001) were predictors of positive hearing outcome. Modiolar abnormalities, cochlear aperture diameter, cochlear malformations, vestibular malformations, and nerves in the cerebellar cistern did not predict hearing outcome (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u2009.79, .18, .59, .09, .17, respectively). For patients who received CI, health status (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u2009.018), IAC midpoint (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u2009.024), and number of nerves in the IAC (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u2009.038) were significant. When controlling for health status, IAC midpoint diameter (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u2009.001) and number of nerves in the IAC (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u2009.001) remained significant. In our cohort, one out of the eight ears (13%) with Birman class 0 or 1 exhibited responses to sound compared to nine out of 13 ears (70%) with Birman class 2\u20134.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Current imaging modalities cannot accurately depict the status of the cochleovestibular nerve or predict a child's benefit with a CI. Cochlear implantation should be considered in children with abnormal cochleovestibular nerves.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      3\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 132:S1\u2013S15, 2022\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.30008","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T09:43:57Z","timestamp":1641807837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Can Imaging Predict Hearing Outcomes in Children With Cochleovestibular Nerve Abnormalities?"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-1695","authenticated-orcid":false,"given":"Elina","family":"Kari","sequence":"first","affiliation":[{"name":"Otolaryngology\u2014Head and Neck Surgery University of California San Diego  San Diego California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle M.","family":"Gillard","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2014Head and Neck Surgery University of California San Diego  San Diego California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel","family":"Chuang","sequence":"additional","affiliation":[{"name":"Radiology Rady Children's Hospital  San Diego California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John L.","family":"Go","sequence":"additional","affiliation":[{"name":"Radiology Keck School of Medicine of University of Southern California  Los Angeles California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320460504"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yped.2010.12.094"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00025"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22032"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910000310"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.202.3.9051033"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000997"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488793"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110021"},{"key":"e_1_2_6_11_1","first-page":"618","article-title":"3\u2010T 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