{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:05:08Z","timestamp":1791889508107,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>To assess whether early, significant improvements in sound source localization observed in cochlear implant (CI) recipients with normal hearing (NH) in the contralateral ear are maintained after 5\u2009years of CI use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective, repeated measures study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were recruited from a sample of CI\u2009+\u2009NH listeners (n\u00a0=\u00a020) who received their device as part of a prospective clinical trial investigating outcomes of CI use for adult cases of single\u2010sided deafness. Sound source localization was assessed annually after the clinical trial endpoint (1\u2010year post\u2010activation). Listeners were asked to indicate the perceived sound source for a broadband noise burst presented randomly at varied intensity levels from one of 11 speakers along a 180\u00b0 arc. Performance was quantified as root\u2010mean\u2010squared (RMS) error.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Linear mixed models showed superior post\u2010activation performance was maintained with long\u2010term CI use as compared to preoperative abilities (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Unexpectedly, a significant improvement (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.009) in sound source localization was observed over the long\u2010term post\u2010activation period (1\u20135\u2009years). To better understand these long\u2010term findings, the response patterns for the 11 participants who were evaluated at the 1\u2010 and 5\u2010year visits were reviewed. This subgroup demonstrated a significant improvement in RMS error (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.020) and variable error (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.031), indicating more consistent responses at the 5\u2010year visit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adult CI\u2009+\u2009NH listeners experience significant improvements in sound source localization within the initial weeks of listening experience, with additional improvements observed after long\u2010term device use. The present sample demonstrated significant improvements between the 1\u2010year and 5\u2010year visits, with greater accuracy and consistency noted in their response patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      3\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 132:2453\u20132458, 2022\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.30065","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T05:33:00Z","timestamp":1645075980000},"page":"2453-2458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["<scp>Long\u2010Term<\/scp>\n                    Improvement in Localization for Cochlear Implant Users with\n                    <scp>Single\u2010Sided<\/scp>\n                    Deafness"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5426-4883","authenticated-orcid":false,"given":"Nicholas J.","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4344-283X","authenticated-orcid":false,"given":"Margaret T.","family":"Dillon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Division of Speech and Hearing Sciences, Department of Allied Health Sciences University of North Carolina at Chapel Hill  North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Buss","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith A.","family":"Rooth","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret E.","family":"Richter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Division of Speech and Hearing Sciences, Department of Allied Health Sciences University of North Carolina at Chapel Hill  North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold C.","family":"Pillsbury","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5709-8702","authenticated-orcid":false,"given":"Kevin D.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(94)90053-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1044\/1092-4388(2011\/10-0205)"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e3182503e5e"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-1147-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/000164580310001105"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31817dad20"},{"key":"e_1_2_6_9_1","unstructured":"U.S. Food and Drug Administration Center for Devices and Radiological Health.MED\u2010EL Cochlear implant system for expanding the indications to include single\u2010sided deafness and asymmetric hearing loss. April2019."},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000430"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000375394"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216518771173"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-016-0297-5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000708"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318268d52d"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000671"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000102"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12555"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001043"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2018.04.004"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1044\/2019_JSLHR-H-18-0409"},{"key":"e_1_2_6_22_1","unstructured":"R Core Team.R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing.2020."},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.394282"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e31806dc21a"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992020600782626"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.2024170"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.4820889"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06450-5"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.30065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:29:03Z","timestamp":1773001743000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.30065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,17]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/lary.30065"],"URL":"https:\/\/doi.org\/10.1002\/lary.30065","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,17]]},"assertion":[{"value":"2021-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}