{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T05:08:15Z","timestamp":1785906495002,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the feasibility, efficacy, and safety of an endoscopic transethmoidal\u2010sphenoidal approach in removing a small cavernous hemangioma (CH) located in the deep lateral orbital apex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study involved 19 patients diagnosed with a CH located in the deep lateral orbital apex. All patients underwent an endoscopic transethmoidal\u2010sphenoidal approach for removal of the CH. The best\u2010corrected visual acuity (BCVA), visual field, and surgery\u2010related complications were analyzed and compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All tumors in this study were completely removed. The mean BCVA was LogMAR 0.97\u2009\u00b1\u20090.97 preoperatively and LogMAR 0.38\u2009\u00b1\u20090.64 postoperatively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The mean visual field index was 52.26%\u2009\u00b1\u200933.26% preoperatively and 75.47%\u2009\u00b1\u200930.49% postoperatively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The mean deviation index was \u221217.48\u2009\u00b1\u200912.43\u2009dB preoperatively and \u221210.10\u2009\u00b1\u200910.85\u2009dB postoperatively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), and the pattern standard deviation was 6.37\u2009\u00b1\u20093.77\u2009dB preoperatively and 4.90\u2009\u00b1\u20093.56\u2009dB postoperatively (<jats:italic>p\u2009&gt;<\/jats:italic>\u00a00.05). Four (21.1%) patients developed oculomotor limitations and two (10.5%) patients developed ptosis after surgery. All of these symptoms resolved spontaneously, and no other complications occurred. The mean follow\u2010up time was 6.71\u2009\u00b1\u20093.89\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The endoscopic transethmoidal\u2010sphenoidal approach is an effective and minimally invasive treatment for removing small CH in the deep lateral orbital apex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 132:1743\u20131749, 2022<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30131","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T11:59:01Z","timestamp":1649246341000},"page":"1743-1749","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Removal of Small Cavernous Hemangioma in Orbital Apex Through an Endoscopic Transethmoidal\u2010Sphenoidal Approach"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5358-4471","authenticated-orcid":false,"given":"Guangming","family":"Zhou","sequence":"first","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6796-6887","authenticated-orcid":false,"given":"Zhaoqi","family":"Pan","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhai","family":"Tu","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0836-9692","authenticated-orcid":false,"given":"Bo","family":"Yu","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2245-7004","authenticated-orcid":false,"given":"Jieliang","family":"Shi","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ende","family":"Wu","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1466-2721","authenticated-orcid":false,"given":"Wencan","family":"Wu","sequence":"additional","affiliation":[{"name":"The Department of Orbital and Oculoplastic Surgery The Eye Hospital of Wenzhou Medical University  Wenzhou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/01676830.2014.915329"},{"issue":"1","key":"e_1_2_6_3_1","first-page":"12","article-title":"Round\u2010the\u2010clock\u201d surgical access to the orbit","volume":"76","author":"Paluzzi A","year":"2015","journal-title":"J Neurol Surg B Skull Base"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2009.08.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2827491"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.05.001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.09.022"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2020.1832123"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000215"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21645"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-19970701-16"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22383"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31822e82b5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21320"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01794679"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.7.GKS10857"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2015.03.001"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.147"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2012-302900"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2012.10.029"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0b013e318177f12c"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1374063"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.03.011"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30131","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.30131","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T22:04:02Z","timestamp":1692741842000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.30131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1002\/lary.30131"],"URL":"https:\/\/doi.org\/10.1002\/lary.30131","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,6]]},"assertion":[{"value":"2021-12-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}