{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:48:13Z","timestamp":1789649293242,"version":"4.0.0"},"reference-count":58,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the effectiveness of Eustachian tube procedures for the treatment of baro\u2010challenge Eustachian tube dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) guidelines, databases, including PubMed (National Library of Medicine, National Institutes of Health), Scopus (Elsevier), and CINAHL (EBSCO), were searched for articles examining the effectiveness of Eustachian tube procedures for baro\u2010challenge Eustachian tube dysfunction. Outcome measures included symptom resolution, ability to return to work, equalization problems (EP) scores, Eustachian Tube Dysfunction Questionnaire (ETDQ\u20107) scores, and pressure chamber testing parameters. Pooled meta\u2010analysis was performed for dichotomous measures and ETDQ\u20107 scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eleven articles with 81 patients were included. Seventy\u2010two patients from 10 articles underwent balloon Eustachian tube dilation; nine patients in 1 study underwent laser Eustachian tuboplasty (LET). All 81 patients were preoperatively symptomatic with barometric pressure change, and 26\/30 (86.7%) were unable to work due to symptoms. On meta\u2010analysis, after balloon dilation Eustachian tuboplasty (BDET), 82.5% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a030 [95% confidence interval: 42%\u2013100%]) had improvement in ability to valsalva, 79.1% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a016 [57.9%\u201394.1%]) in ability to return to work, and 84.3% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a069 [69.8%\u201394.7%]) in any symptom. Of 25 patients with individual ETDQ\u20107 scores, 79.1% [51.4, 96.9] had improvements after BDET. For four case series with 36 patients, ETDQ\u20107 scores decreased by 1.2 [0.7, 1.7] (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001). Of 20 patients with preoperative ETDQ\u20107 scores &gt;2.0, there was a mean decrease of 2.1 [1.3, 2.8] (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      From the available evidence, Eustachian tube procedures appear to be effective at improving symptoms of baro\u2010challenge Eustachian tube dysfunction. However, higher quality evidence is needed to support making definite recommendations for the use of balloon Eustachian tube dilation or LET for these patients.\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 132:2473\u20132483, 2022\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.30132","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T08:34:05Z","timestamp":1650443645000},"page":"2473-2483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["A Systematic Review of Eustachian Tube Procedures for Baro\u2010challenge Eustachian Tube Dysfunction"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7252-1476","authenticated-orcid":false,"given":"Mallory J.","family":"Raymond","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2972-637X","authenticated-orcid":false,"given":"Michael C.","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip Ryan","family":"Elvis","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0664-4571","authenticated-orcid":false,"given":"Shaun A.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Research and Education Services Medical University of South Carolina Libraries  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted A.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina 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