{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:30:44Z","timestamp":1747150244136,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>End\u2010flexible\u2010rigidscopic transoral surgery (E\u2010TOS) is a new and minimally invasive transoral surgery for resection of Tis\u2010selected T3 pharyngolaryngeal cancers. We evaluated long\u2010term oncological outcomes and whether postoperative voice and swallowing function were preserved following E\u2010TOS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective single\u2010center study, 154 patients treated with E\u2010TOS using a curved retractor, flexible\u2010tip rigid endoscope, and thin curved instruments were included. Their survival rate, larynx preservation rate, and disease control rate were estimated using the Kaplan\u2013Meier method. Postoperative voice function was evaluated using both objective and subjective tests. Postoperative swallowing function was assessed using the Hyodo score and the functional outcome swallowing scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 3\u2010year and 5\u2010year overall survival, disease\u2010specific survival, disease\u2010free survival, laryngectomy\u2010free survival, local control, and loco\u2010regional control rates post E\u2010TOS were 89.8% and 82.2%, 95.6% and 92.3%, 78.5% and 70.3%, 87.2% and 80.9%, 93.9% and 92.5%, and 87.2% and 85.7%, respectively. Both objective and subjective postoperative voice and swallowing function tests were within normal limits in more than 90% of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>E\u2010TOS is an effective, safe, low\u2010cost, and minimally invasive transoral surgery for Tis\u2010selected T3 pharyngolaryngeal cancer; it also preserves postoperative voice, larynx, and swallowing function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 133:1415\u20131424, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30316","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T08:49:36Z","timestamp":1659516576000},"page":"1415-1424","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>Long\u2010Term<\/scp> Outcomes of <scp>End\u2010Flexible\u2010Rigidscopic<\/scp> Transoral Surgery for Pharyngolaryngeal Cancer"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8088-0420","authenticated-orcid":false,"given":"Yoshiki","family":"Watanabe","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery Japanese Red Cross Osaka Hospital  Osaka Japan"},{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinzo","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery Uji\u2010Tokushukai Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2555-0511","authenticated-orcid":false,"given":"Koki","family":"Hasebe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Hiratsuka","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery Japanese Red Cross Osaka Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head &amp; 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