{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T05:17:31Z","timestamp":1780550251106,"version":"3.54.1"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003354","name":"Garnett Passe and Rodney Williams Memorial Foundation","doi-asserted-by":"publisher","award":["Conjoint Research Grant"],"award-info":[{"award-number":["Conjoint Research Grant"]}],"id":[{"id":"10.13039\/501100003354","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Recent evidence suggests that detection of nasal mucosal temperature, rather than direct airflow detection, is the primary determinant of subjective nasal patency. This study examines the role of nasal mucosal temperature in the perception of nasal patency using in vivo and computational fluid dynamics (CFD) measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Healthy adult participants completed Nasal Obstruction Symptom Evaluation (NOSE) and Visual Analogue Scale (VAS) questionnaires. A temperature probe measured nasal mucosal temperature at the vestibule, inferior turbinate, middle turbinate, and nasopharynx bilaterally. Participants underwent a CT scan, used to create a 3D nasal anatomy model to perform CFD analysis of nasal mucosal and inspired air temperature and heat flux along with mucosal surface area where heat flux &gt;50\u2009W\/m<jats:sup>2<\/jats:sup> (SAHF50).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven participants with a median age of 27 (IQR 24; 48) were recruited. Probe\u2010measured temperature values correlated strongly with CFD\u2010derived values (<jats:italic>r<\/jats:italic>\u00a0=\u20090.87, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.05). Correlations were seen anteriorly in the vestibule and inferior turbinate regions between nasal mucosal temperature and unilateral VAS (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.42\u20130.46; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), between SAHF50 and unilateral VAS (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.31 to \u22120.36; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and between nasal mucosal temperature and SAHF50 (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.37 to \u22120.41; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Subjects with high patency (VAS \u226410) had increased heat flux anteriorly compared with lower patency subjects (VAS &gt;10; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Lower nasal mucosal temperature and higher heat flux within the anterior nasal cavity correlates with a perception of improved unilateral nasal patency in healthy individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 133:1328\u20131335, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30327","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T09:57:32Z","timestamp":1659520652000},"page":"1328-1335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Correlation of Nasal Mucosal Temperature and Nasal Patency\u2014A Computational Fluid Dynamics 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