{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:28:08Z","timestamp":1785198488342,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002548"],"award-info":[{"award-number":["UL1TR002548"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate how often patients are diagnosed with new\u2010onset tinnitus within 21\u2009days after COVID\u201019 vaccination in comparison to after three other common vaccinations: influenza, Tdap (tetanus, diphtheria, and acellular pertussis), and polysaccharide pneumococcus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The TriNetX Analytics Network, a federated health research network that aggregates the de\u2010identified electronic health record (EHR) data of over 78\u2009million patients, was queried for patients receiving each vaccination. Instances of new\u2010onset tinnitus within 21\u2009days of vaccination were recorded and reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 2,575,235 patients receiving a first dose of the mRNA COVID\u201019 vaccine without any prior tinnitus diagnosis, 0.038% (95% CI: 0.036%\u20130.041%) of patients had a new diagnosis of tinnitus within 21\u2009days. There was a higher risk of a new tinnitus diagnosis after the influenza vaccine (RR: 1.95, 95% CI: 1.72\u20132.21), Tdap vaccine (RR: 2.36, 95% CI: 1.93\u20132.89), and pneumococcal vaccine (RR: 1.97, 95% CI: 1.48\u20132.64) than after the first dose of the COVID\u201019 vaccine. There was a lower risk of a new tinnitus diagnosis after the second dose of COVID\u201019 than after the first dose (RR: 0.80, 95% CI: 0.71\u20130.91).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The rate of newly diagnosed tinnitus acutely after the first dose of the COVID\u201019 vaccine is very low. There was a higher risk of newly diagnosed tinnitus after influenza, Tdap, and pneumococcal vaccinations than after the COVID\u201019 vaccine. The present findings can help to address COVID\u201019 vaccine hesitancy during the ongoing pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>Level 3 <jats:italic>Laryngoscope<\/jats:italic>, 133:1722\u20131725, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30395","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T12:18:05Z","timestamp":1663071485000},"page":"1722-1725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of <scp>New\u2010Onset<\/scp> Tinnitus after <scp>COVID<\/scp>\u201019 Vaccination with Comparison to Other Vaccinations"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2520-0557","authenticated-orcid":false,"given":"Ian","family":"Dorney","sequence":"first","affiliation":[{"name":"School of Medicine Case Western Reserve University  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Bobak","sequence":"additional","affiliation":[{"name":"School of Medicine Case Western Reserve University  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Otteson","sequence":"additional","affiliation":[{"name":"School of Medicine Case Western Reserve University  Cleveland Ohio USA"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University Hospitals Cleveland Medical Center  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Kaelber","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine, Pediatrics, and Population and Quantitative Health Sciences Case Western Reserve University  Cleveland Ohio USA"},{"name":"The Center for Clinical Informatics Research and Education The MetroHealth System  Cleveland Ohio 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