{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:28:13Z","timestamp":1791412093975,"version":"4.3.3"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Assess the long\u2010term patterns of perceived tinnitus severity and subjective benefit for adult cochlear implant (CI) users with asymmetric or unilateral hearing loss (AHL or UHL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty adults underwent cochlear implantation as part of a prospective clinical trial assessing the outcomes of CI use in cases of AHL (<jats:italic>n<\/jats:italic>\u00a0=\u00a020) and UHL (<jats:italic>n<\/jats:italic>\u00a0=\u00a020). Subjective measures included the Tinnitus Handicap Inventory (THI), the Speech, Spatial, &amp; Qualities of Hearing Scale (SSQ), and the Abbreviated Profile of Hearing Aid Benefit (APHAB). Responses were obtained preoperatively and at routine intervals out to 5\u2009years post\u2010activation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For subjective benefit, participants with AHL and UHL reported a significant improvement as compared to preoperative abilities, which was maintained with long\u2010term CI use. For perceived tinnitus severity, participants with AHL and UHL reported a significant reduction with CI use as compared to preoperative perceptions. The perceived tinnitus severity significantly differed for the AHL and UHL cohorts over time. This pattern of results is likely influenced by the worse perceived severity levels for the UHL cohort preoperatively and the fluctuating perceived severity levels for some participants in the AHL cohort post\u2010activation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Adults with AHL and UHL report an early, significant reduction in perceived tinnitus severity and improvement in quality of life with CI use that is generally maintained with long\u2010term device use. Questionnaires such as the THI, SSQ, and APHAB may contribute to a more holistic assessment of the benefits of cochlear implantation in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2 <jats:italic>Laryngoscope<\/jats:italic>, 133:2792\u20132797, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30608","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T11:54:52Z","timestamp":1675943692000},"page":"2792-2797","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Cochlear Implantation for Unilateral and Asymmetric Hearing Loss: <scp>Long\u2010Term<\/scp> Subjective Benefit"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5426-4883","authenticated-orcid":false,"given":"Nicholas J.","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4636-055X","authenticated-orcid":false,"given":"Erin M.","family":"Lopez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4344-283X","authenticated-orcid":false,"given":"Margaret T.","family":"Dillon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith A.","family":"Rooth","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret E.","family":"Richter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold C.","family":"Pillsbury","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5709-8702","authenticated-orcid":false,"given":"Kevin D.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head &amp; Neck Surgery, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"772","article-title":"Unilateral deafness in adults: effects on communication and social interaction","volume":"119","author":"Wie OB","year":"2010","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992020400050033"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819846084"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000681"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.4802.150"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216518813802"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22145"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e3182a3648b"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820911716"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003261"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000484079"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488755"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181fcf271"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1044\/1059-0889(2009\/07-0042)"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002711"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940811700903"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31828779f0"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5135-9"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28358"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000171478"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e31824b9dfc"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216518771173"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216520945524"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002235"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2015.09.016"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992020400050014"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/14992027.2013.781278"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199012000-00005"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30065"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1159\/000523969"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30065"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890140029007"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1044\/2019_JSLHR-H-18-0409"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199504000-00005"},{"key":"e_1_2_8_36_1","article-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2020","journal-title":"R Foundation for Statistical Computing"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1044\/2019_AJA-19-00045"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.30608","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T18:59:35Z","timestamp":1695149975000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.30608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,9]]},"references-count":36,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/lary.30608"],"URL":"https:\/\/doi.org\/10.1002\/lary.30608","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,9]]},"assertion":[{"value":"2022-08-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}