{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:21:02Z","timestamp":1784665262130,"version":"3.55.0"},"reference-count":55,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>A deviated nasal septum (DNS) can result in an anatomical obstruction and impact lung function through prolonged suboptimal inspiration. Given the improvements in respiration reported by patients following septoplasty or septorhinoplasty (with or without inferior turbinate reduction), our study investigated the effect of these procedures on pulmonary function through a systematic review and meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>Medline, Embase, Cochrane Databases, Web of Science, and Google Scholar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Review Methods<\/jats:title><jats:p>The review was registered with PROSPERO [CRD42022316309]. The study population was composed of adult patients (18\u201365) who were symptomatic with confirmed DNS. Extracted outcomes (pre\u2010operative versus postoperative) included the six\u2010minute walk test (6MWT) and pulmonary function tests (FEV1, FVC, FEV1\/FVC, FEF25\u201075, PEF). Meta\u2010analyses were performed using a random\u2010effects model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three studies included measures of the 6MWT in meters and all three found a statistically significant increase in the distance walked after surgery with a mean difference of 62.40\u2009m (95% CI 24.79\u2013100.00). Statistically significant improvements in PFT outcomes were observed with a standard mean difference of 0.72 for FEV1 (95% CI 0.31\u20131.13), 0.63 for FVC (95% CI 0.26\u20131.00), and 0.64 for PEF (95% CI 0.47\u20130.82). Of the twelve studies which measured PFT outcomes, six showed statistically significant improvements, three studies showed mixed results, and three studies found no difference in PFT outcomes between pre\u2010and post\u2010surgery testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study suggests that pulmonary function does improve after nasal surgery for DNS, but the high heterogeneity observed in the meta\u2010analyses indicates that the evidence supporting this conclusion is low. <jats:italic>Laryngoscope<\/jats:italic>, 133:2837\u20132845, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30651","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T11:38:12Z","timestamp":1678448292000},"page":"2837-2845","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Effects of Nasal Surgery on Pulmonary Function: A Systematic Review and 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