{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T14:20:50Z","timestamp":1778854850759,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:00:00Z","timestamp":1680652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The long\u2010term impact of rhinitis and chronic rhinosinusitis (CRS) on general health and medical services utilization in young adults have been limitedly studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case\u2013control study in the Israeli Defense Forces, between the years 2005 and 2019, of all individuals with either rhinitis or CRS and a matched cohort of healthy individuals with a minimum of 5\u2009years of consecutive follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study groups included 617 patients with rhinitis and 296 patients with CRS and 2739 healthy controls with an average age of 28\u2009years. During a mean follow\u2010up of 8\u2009years, a significant fraction of patients in both study groups were diagnosed with asthma compared to the control group, (26.1% and 23.3% vs. 3.7%, respectively; CI 95%: 12.1%\u201314.9%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). 7.6% of patients with rhinitis developed CRS. Significantly increased loss of productivity and medical system utilization were noted in the study groups compared to controls (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Moreover, deterioration in general health, manifested as loss of physical fitness for combative service was observed in a third of patients during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Rhinitis and CRS significantly impact productivity and medical service utilization in young adults, as well as general health associated with development of asthma and impairment of physical fitness. A minority of rhinitis patients develop CRS overtime, further affecting this patient group. These patients should be followed up and managed to improve disease control and associated outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 133:3299\u20133303, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30685","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T11:04:37Z","timestamp":1680692677000},"page":"3299-3303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The <scp>Long\u2010Term<\/scp> Implications of Rhinitis and Chronic Rhinosinusitis in Young Adults"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8161-8034","authenticated-orcid":false,"given":"Yoni","family":"Shopen","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery Rabin Medical Center \u2013 Beilinson Hospital  Petach\u2010Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2178-8971","authenticated-orcid":false,"given":"Nir","family":"Tsur","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery Rabin Medical Center \u2013 Beilinson Hospital  Petach\u2010Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Medical Corps Israel Defense Forces  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4846-7614","authenticated-orcid":false,"given":"Ethan","family":"Soudry","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery Rabin Medical Center \u2013 Beilinson Hospital  Petach\u2010Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv 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