{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:58:28Z","timestamp":1793393908377,"version":"4.5.0"},"reference-count":45,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81900940"],"award-info":[{"award-number":["81900940"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020MH179"],"award-info":[{"award-number":["ZR2020MH179"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ts20130913"],"award-info":[{"award-number":["ts20130913"]}],"id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The study goals were to compare the long\u2010term efficacy of semicircular canal plugging (SCP) with labyrinthectomy in the treatment of advanced Meniere's disease (MD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single tertiary medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 116 MD patients (TSCP group of 90; labyrinthectomy group of 26) with complete medical documents in Shandong Provincial ENT Hospital, from March 2017 to March 2019 were retrospectively analyzed, including a battery of auditory and vestibular function tests, recovery time from imbalance and function level scores (FLS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total control rate of vertigo in the TSCP group was 96.7% (87\/90). The rate of hearing loss was 23.3% (21\/90). The control rate of vertigo in the labyrinthectomy group was 100% (26\/26). All patients lost their auditory function after labyrinthectomy with a 100% hearing loss rate. There was no significant difference in the vertigo control rate between the two groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). The hearing loss rate in the TSCP group was significantly lower than that in the labyrinthectomy group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00). The median time recovered from imbalance was 15\u2009days in TSCP group and 21\u2009days in labyrinthectomy group, which is significantly different (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). There was no significant difference in the FLS between the two groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared to labyrinthectomy, TSCP can preserve hearing at a high probability; meanwhile, otolith organ function preservation benefits patients from faster vestibular compensation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 133:3178\u20133184, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30690","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T11:30:25Z","timestamp":1681126225000},"page":"3178-3184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Triple Semicircular Canal Plugging versus Labyrinthectomy for Meniere Disease: A Retrospective Study"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6968-6256","authenticated-orcid":false,"given":"Xiaofei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0620-574X","authenticated-orcid":false,"given":"Yafeng","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huirong","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongdong","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ligang","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaomin","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0955-9532","authenticated-orcid":false,"given":"Haibo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2446-1595","authenticated-orcid":false,"given":"Daogong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Shandong Provincial ENT Hospital, Shandong University  Jinan 250022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200402000-00004"},{"issue":"2","key":"e_1_2_9_3_1","first-page":"S1","article-title":"Clinical practice guideline: Meniere's disease","volume":"162","author":"Basura GJ","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199307000-00007"},{"key":"e_1_2_9_5_1","first-page":"505","article-title":"Meniere's disease. 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