{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:31:51Z","timestamp":1747150311428,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>There has been a notable increase in the number of neonates born 28\u2009weeks gestational age or younger in the United States. Many of these patients require tracheostomy early in life and subsequent laryngotracheal reconstruction (LTR). Although extremely premature infants often undergo LTR, there is no known study to date examining their post\u2010surgical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare decannulation rates, time to decannulation and complication rates between LTR patients born extremely premature to those born preterm and term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified 179 patients treated at a stand\u2010alone tertiary children's hospital who underwent open airway reconstruction from 2008 to 2021. A Chi Squared test was used to detect differences in categorical clinical data between the groups of patients. A Mann\u2013Whitney test was used to analyze continuous data within these same groups. Time to decannulation analysis was performed using Kaplan Meier analysis and evaluated with log\u2010rank and Cox proportional hazards regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Children born extremely premature were more likely to incur complications following LTR (OR\u2009=\u20092.363, <jats:italic>p<\/jats:italic>\u2009=\u20090.005, CI 1.295\u20134.247). There was no difference in time to decannulation (<jats:italic>p<\/jats:italic>\u2009=\u20090.0543, Log\u2010rank) or rate of decannulation (OR\u2009=\u20090.4985, <jats:italic>p<\/jats:italic>\u2009=\u20090.05, CI 0.2511\u20131.008). Extremely premature infants were more likely to be treated with an anterior and posterior grafts (OR\u2009=\u20092.471, <jats:italic>p<\/jats:italic>\u2009=\u20090.004, CI 1.297\u20134.535) and\/or an airway stent (OR\u2009=\u20093.112, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, CI 1.539\u20135.987).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared with all other patients, extremely premature infants have equivalent decannulation success, but are at an increased risk for complications following LTR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 133:3608\u20133614, 2023<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30716","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T13:08:07Z","timestamp":1682514487000},"page":"3608-3614","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laryngotracheal Reconstruction Outcomes in Children Born Extremely Premature"],"prefix":"10.1002","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6291-0726","authenticated-orcid":false,"given":"Daniel","family":"Blumenthal","sequence":"first","affiliation":[{"name":"Department of Pediatric Otolaryngology Children's National Medical Center  Washington District of Columbia U.S.A."},{"name":"Department of Otolaryngology and Head and Neck Surgery Residency Medstar Georgetown University Hospital  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7955-0392","authenticated-orcid":false,"given":"James A.","family":"Leonard","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Children's National Medical Center  Washington District of Columbia U.S.A."},{"name":"Department of Otolaryngology and Head and Neck Surgery Residency Medstar Georgetown University Hospital  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3366-8528","authenticated-orcid":false,"given":"Andy","family":"Habib","sequence":"additional","affiliation":[{"name":"Georgetown University School of Medicine  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0050-8336","authenticated-orcid":false,"given":"Hengameh","family":"Behzadpour","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Children's National Medical Center  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Espinel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Children's National Medical Center  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0075-8279","authenticated-orcid":false,"given":"Diego","family":"Preciado","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Children's National Medical Center  Washington District of Columbia U.S.A."},{"name":"George Washington University School of Medicine  Washington District of Columbia U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2021-055924"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000705"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2012.03.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28304"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1984.tb02035.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599810392180"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.05.034"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2010.12.017"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199508000-00009"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199311000-00011"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-5876(99)00235-9"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2020.03.024"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28864"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28297"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24596"},{"key":"e_1_2_6_17_1","unstructured":"Median income in the past 12 months. 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