{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T03:13:44Z","timestamp":1789269224309,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81271084"],"award-info":[{"award-number":["81271084"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81420108010"],"award-info":[{"award-number":["81420108010"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81700915"],"award-info":[{"award-number":["81700915"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Our team designed a long\u2010lasting, well\u2010sealed microphone, which uses laser welding and vacuum packaging technology. This study examined the sensitivity and effectiveness of this new floating piezoelectric microphone (NFPM) designed for totally implantable cochlear implants (TICIs) in animal experiments and intraoperative testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Different NFPM frequency responses from 0.25 to 10\u2009kHz at 90\u2009dB SPL were analyzed using in vivo testing of cats and human patients. The NFPM was tested in different positions that were clamped to the ossicular chains or placed in the tympanic cavity of cats and human patients. Two volunteers' long incus foot and four cats' malleus neck of the ossicular chain were clamped with the NSFM. The output electrical signals from different locations were recorded, analyzed, and compared. The NFPM was removed after the test without causing any damage to the middle\u2010ear structure of the cats. Intraoperative tests of the NFPM were performed during the cochlear implant surgery and the cochlear implant surgery was completed after all tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with the results in the tympanic cavity, the NFPM could detect the vibration from the ossicular chain more sensitively in cat experiments and intraoperative testing. We also found that the signal output level of the NFPM decreased as the acoustic stimulation strength decreased in the intraoperative testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The NFPM is effective in the intraoperative testing, making it feasible as an implantable middle\u2010ear microphone for TICIs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:937\u2013944, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30861","type":"journal-article","created":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T11:06:54Z","timestamp":1688814414000},"page":"937-944","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A New Floating Piezoelectric Microphone for Fully Implantable Cochlear Implants in Middle Ear"],"prefix":"10.1002","volume":"134","author":[{"given":"Xin\u2010Da","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Otology and Skull Base Surgery, Eye Ear Nose &amp; Throat Hospital Fudan University  Shanghai China"},{"name":"Shanghai Auditory Medical Center  Shanghai China"},{"name":"NHC Key Laboratory of Hearing Medicine (Fudan University)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9272-1398","authenticated-orcid":false,"given":"Wei\u2010Xun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otology and Skull Base Surgery, Eye Ear Nose &amp; Throat Hospital Fudan University  Shanghai China"},{"name":"Shanghai Auditory Medical Center  Shanghai China"},{"name":"NHC Key Laboratory of Hearing Medicine (Fudan University)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian\u2010Hao","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Otology and Skull Base Surgery, Eye Ear Nose &amp; Throat Hospital Fudan University  Shanghai China"},{"name":"Shanghai Auditory Medical Center  Shanghai China"},{"name":"NHC Key Laboratory of Hearing Medicine (Fudan University)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong\u2010Zhen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Otology and Skull Base Surgery, Eye Ear Nose &amp; 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