{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T13:26:06Z","timestamp":1774445166572,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Nasal airway obstruction (NAO) is caused by various disorders including nasal valve collapse (NVC). A bipolar radiofrequency (RF) device (VivAer\u00ae, Aerin Medical, Sunnyvale, CA) has been used to treat NAO through RF heat generation to the upper lateral cartilage (ULC). The purpose of this study is to measure temperature elevations in nasal tissue, using infrared (IR) radiometry to map the spatial and temporal evolution of temperature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Experimental and computational.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Composite porcine nasal septum was harvested and sectioned (1\u2009mm and 2\u2009mm). The device was used to heat the cartilage in composite porcine septum. An IR camera (FLIR\u00ae ExaminIR, Teledyne, Wilsonville, OR) was used to image temperature on the back surface of the specimen. These data were incorporated into a heat transfer finite element model that also calculated tissue damage using Arrhenius rate process.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>IR temperature imaging showed peak back surface temperatures of 49.57\u00b0C and 42.21\u00b0C in 1 and 2\u2009mm thick septums respectively. Temperature maps were generated demonstrating the temporal and spatial evolution of temperature. A finite element model generated temperature profiles with respect to time and depth. Rate process models using Arrhenius coefficients showed 30% chondrocyte death at 1\u2009mm depth after 18\u2009s of RF treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of this device creates a thermal profile that may result in thermal injury to cartilage. Computational modeling suggests chondrocyte death extending as deep as 1.4\u2009mm below the treatment surface. Further studies should be performed to improve dosimetry and optimize the heating process to reduce potential injury. <jats:italic>Laryngoscope<\/jats:italic>, 134:1063\u20131070, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30942","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T21:12:56Z","timestamp":1692652376000},"page":"1063-1070","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Temperature Profile Measurement From Radiofrequency Nasal Airway Reshaping Device"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0905-0656","authenticated-orcid":false,"given":"Eric H.","family":"Abello","sequence":"first","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of California \u2013 Irvine Medical Center  Orange California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3416-5976","authenticated-orcid":false,"given":"Theodore V.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3034-5662","authenticated-orcid":false,"given":"Katelyn K.","family":"Dilley","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donggyoon","family":"Hong","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pranav S.","family":"Nair","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin F.","family":"Bitner","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of California \u2013 Irvine Medical Center  Orange California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wangcun","family":"Jia","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian J. F.","family":"Wong","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic  Irvine California USA"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of California \u2013 Irvine Medical Center  Orange California USA"},{"name":"Department of Biomedical Engineering Henry Samueli School of Engineering  Irvine California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200307000-00004"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27859"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198301000-00009"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2018.05.001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.04.019"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240301700208"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240401800303"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.2000.15e20.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002341-200101000-00012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.6.3.167"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-954845"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20495"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200105000-00025"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.247"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23019"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.135"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-003-0275-5"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.429896"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20611"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10167"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9101(2000)27:2<119::aid-lsm3>3.0.co;2-v"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-6092-7_17"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/48\/1\/302"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1109\/2944.983298"},{"key":"e_1_2_6_26_1","doi-asserted-by":"crossref","unstructured":"Diaz\u2010ValdesSH AguilarG BasuR LaverniaEJ WongBJ.Modeling the thermal response of porcine cartilage to laser irradiation. In: Jacques SL Duncan DD Kirkpatrick SJ Kriete A eds; 2002:47\u201356.https:\/\/doi.org\/10.1117\/12.472507.","DOI":"10.1117\/12.472507"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.67.10.1708"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2002.29893"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20663"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22057"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900130607"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2013.6.2.82"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200104000-00012"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659702500421"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.8.2.105"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011365"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100130403"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2001.21903"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900050606"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3205\/CTO000071"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-05270-y"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065801781543790"},{"key":"e_1_2_6_43_1","unstructured":"IT'IS Foundation.Tissue Properties Database V4.1. Published online 2022.https:\/\/doi.org\/10.13099\/VIP21000-04-1."}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.30942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T12:32:32Z","timestamp":1708086752000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.30942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,18]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1002\/lary.30942"],"URL":"https:\/\/doi.org\/10.1002\/lary.30942","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,18]]},"assertion":[{"value":"2023-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}