{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:39:40Z","timestamp":1787229580944,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T00:00:00Z","timestamp":1692403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to present 2 children clinically diagnosed with periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome and treated with intracapsular tonsillectomy with adenoidectomy (ITA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective analysis of 2 children who were referred for an otolaryngology consultation between 2019 and 2022 for surgical treatment of PFAPA syndrome. Both patients had symptoms strongly suggestive of PFAPA and were at risk for total tonsillectomy (TT) complications. ITA was performed using a microdebrider. Both patients were followed up postoperatively to assess for symptomatic resolution and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two children exhibited recurrent febrile episodes prior to ITA. The procedure was efficacious in both patients, with neither experiencing postoperative complications or recurring PFAPA symptoms for over 1 year after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study reported on the use of ITA as a surgical treatment option for PFAPA. We showed that ITA eliminated febrile attacks and was safely performed without postoperative complications in 2 pediatric patients after 1\u2010year follow\u2010up. Future studies involving larger cohorts of PFAPA patients and lengthier follow\u2010ups will need to be conducted to further evaluate ITA as a surgical option. <jats:italic>Laryngoscope<\/jats:italic>, 134:1967\u20131969, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.30969","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T15:44:22Z","timestamp":1692459862000},"page":"1967-1969","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Management of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis with Intracapsular Tonsillectomy"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8860-6319","authenticated-orcid":false,"given":"Uche C.","family":"Ezeh","sequence":"first","affiliation":[{"name":"Division of Pediatric Otolaryngology, Department of Otolaryngology\u2010Head and Neck Surgery New York University School of Medicine  New York New York U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Kahn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hassenfeld Children's Hospital at NYU Langone Medical Center  New York New York U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0215-5503","authenticated-orcid":false,"given":"Max M.","family":"April","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology, Department of Otolaryngology\u2010Head and Neck Surgery New York University School of Medicine  New York New York 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