{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:02:20Z","timestamp":1787162540537,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,4]]},"abstract":"\n Objective(s)<\/jats:title>\n The aim was to investigate the utilization and efficacy of bilateral superior laryngeal nerve block in patients with refractory chronic cough.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A retrospective chart review of 164 patients with refractory chronic cough who underwent bilateral SLN block at a single institution between November 2018 and September 2022 was performed. Demographics, comorbidities, and patient\u2010reported outcomes including pre\u2010 and postinjection Leicester Cough Questionnaire (LCQ) scores were collected and analyzed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The cohort underwent an average of 2.97 bilateral injections (range 1\u201322), containing either corticosteroid and local anesthetic or corticosteroid alone. Notably, 116 of 164 of patients reported an average of 67.3% reduction in their symptoms, with the treatment effect lasting 7.60\u2009weeks on average. The average pre\u2010 and postinjection LCQ scores were 9.70 and 13.82, respectively. A lower LCQ score represents a greater impairment of health status due to cough, and the minimum important change is 1.3 points between questionnaires. The average improvement on LCQ following bilateral SLN block was 4.11 points for this cohort.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The use of in\u2010office bilateral SLN block is an effective treatment that can be used alone or in conjunction with oral medications for the treatment of refractory chronic cough.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n \n 4\n Laryngoscope<\/jats:italic>\n , 134:1773\u20131777, 2024\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lary.31061","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T07:57:31Z","timestamp":1695715051000},"page":"1773-1777","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["The Role of Bilateral Superior Laryngeal Nerve Block in Managing Refractory Chronic Cough"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4524-612X","authenticated-orcid":false,"given":"Brooke A.","family":"Quinton","sequence":"first","affiliation":[{"name":"Case Western Reserve University School of Medicine Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Tierney","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1908-397X","authenticated-orcid":false,"given":"Michael S.","family":"Benninger","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca C.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Gau","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace M.","family":"Hrelec","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6957-2299","authenticated-orcid":false,"given":"Paul C.","family":"Bryson","sequence":"additional","affiliation":[{"name":"Case Western Reserve University School of Medicine Cleveland Ohio U.S.A."},{"name":"Department of Otolaryngology Cleveland Clinic Cleveland Ohio U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00218714"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25186"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2072-1439.2014.08.41"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PUPT.2017.04.001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.59"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27201"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.292"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13857"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","unstructured":"The Voice Handicap Index (VHI).Development and Validation. Barbara H. Jacobson Alex Johnson Cynthia Grywalski Alice Silbergleit Gary Jaconsen Michael S. Benninger. American Journal of Speech\u2010Language Pathology Vol 6(3) 66\u201370. The Voice Handicap Index is reprinted with permission from all authors and ASHA. Copyright 1997\u20132001 American Speech\u2010Language\u2010Hearing Association.1997.","DOI":"10.1044\/1058-0360.0603.66"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.58.4.339"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0283758"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2012\/15\/E363"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj\/2016.19.E365"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-016-0190-z"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00954"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.31061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T09:03:16Z","timestamp":1719910996000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.31061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/lary.31061"],"URL":"https:\/\/doi.org\/10.1002\/lary.31061","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]},"assertion":[{"value":"2023-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}