{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T01:42:13Z","timestamp":1783734133462,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Recent evidence suggests that environmental factors impact craniofacial development. Specifically, the height and width of the maxilla may impact the degree of septal deviation. We sought to determine the relationship between transverse maxillary deficiency and severity of septal deviation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort of adult sleep surgery patients were evaluated by standardized CT imaging. Primary outcomes evaluated the relationship of a narrow, high\u2010arched palate (the palatal height to width ratio) with the degree of septal deviation at the level of the 1st premolar and 1st molar. Secondary outcome evaluated the relationship of the palatal height\u2010to\u2010width ratio and nasal obstruction. Both adjusted and unadjusted linear regression were performed, including correction for multiple hypothesis testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010three patients were included. On average, the cohort was middle aged (54.7\u2009\u00b1\u200912.7\u2009years), obese (BMI 30.1\u2009\u00b1\u20094.5\u2009kg\/m<jats:sup>2<\/jats:sup>), predominantly male (74.2%), White (73.1%), and with severe obstructive sleep apnea (OSA) (AHI 30.0\u2009\u00b1\u200918.7 events\/h). A moderate correlation was observed between both the relative and absolute <jats:italic>inter\u2010premolar<\/jats:italic> palatal height and the degree of septal deviation at the <jats:italic>inter\u2010molar<\/jats:italic> region. No significant correlation was observed between palatal dimensions and NOSE score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study found that transverse maxillary deficiency is moderately associated with greater degree of septal deviation among a sample of OSA patients. This contributes to the concept that craniofacial development impacts the nasal airway, promoting a comprehensive evaluation of both endonasal and extranasal structures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:2464\u20132470, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31122","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T12:08:16Z","timestamp":1698754096000},"page":"2464-2470","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The Association Between Transverse Maxillary Deficiency and Septal Deviation in Adults with <scp>Obstructive Sleep Apnea<\/scp>"],"prefix":"10.1002","volume":"134","author":[{"given":"Michael J.","family":"Hutz","sequence":"first","affiliation":[{"name":"Section of Sleep Surgery, Department of Otolaryngology \u2013 Head and Neck Surgery Rush University Medical Center  Chicago Illinois U.S.A."},{"name":"Section of Sleep Medicine, Department of Pulmonary, Critical Care and Sleep Medicine Rush University Medical Center  Chicago Illinois U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Thuler","sequence":"additional","affiliation":[{"name":"Division of Sleep Surgery, Department of Otorhinolaryngology \u2013 Head and Neck Surgery Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7238-327X","authenticated-orcid":false,"given":"Crystal","family":"Cheong","sequence":"additional","affiliation":[{"name":"Division of Sleep Surgery, Department of Otorhinolaryngology \u2013 Head and Neck Surgery Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chau","family":"Phung","sequence":"additional","affiliation":[{"name":"University of Pennsylvania, Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Evans","sequence":"additional","affiliation":[{"name":"Division of Sleep Surgery, Department of Otorhinolaryngology \u2013 Head and Neck Surgery Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan T.","family":"Keenan","sequence":"additional","affiliation":[{"name":"Division of Sleep Medicine, Department of Medicine University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5568-0427","authenticated-orcid":false,"given":"Raj C.","family":"Dedhia","sequence":"additional","affiliation":[{"name":"Division of Sleep Surgery, Department of Otorhinolaryngology \u2013 Head and Neck Surgery Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania U.S.A."},{"name":"Department of Radiology University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,31]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"National Ambulatory Medical Care Survey. 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